STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1953Conserved hypothetical secreted protein. Homology to Raeut03000741 of Ralstonia eutropha of 45% (gi|46131405|ref|ZP_00169583.2|(NBCI ENTREZ)). Pfam: Protein of unknown function (DUF1329). This family consists of several hypothetical bacterial proteins of around 475 residues in length. The majority of family members are from Pseudomonas species but the family also contains sequences from Shewanella oneidensis and Thauera aromatica. No TMHs. Signal peptide present; Conserved hypothetical protein. (422 aa)    
Predicted Functional Partners:
azo1952
Conserved hypothetical secreted protein. Homology to Daro03003313 of Dechloromonas aromatica of 60% (gi|53729649|ref|ZP_00149978.2|(NBCI ENTREZ)). Has PF06980, Protein of unknown function (DUF1302);IPR010727,DUF1302;This family contains a number of hypothetical bacterial proteins of unknown function that are approximately 600 residues long. Most family members seem to be from Pseudomonas. Signal peptide present. No TMHs; Conserved hypothetical protein.
 
     0.943
azo1951
Putative exporter of RND superfamily; Probable Putative membrane protein MJ1562. TREMBL:Q8G9A8:32% identity, 52% similarity InterPro:IPR000873; AMP-bind. IPR002114; HPr_SerP_S Pfam:Patched:Patched family 2A067: efflux transporter putative Signal peptide present (Signal P predicted) TMH's 10 (TMHMM predicted); Family membership.
 
   
 0.899
azo1950
Conserved hypothetical membrane protein. Homology to Daro03003315 of Dechloromonas aromatica of 48% (gi|53729651|ref|ZP_00348492.1|(NBCI ENTREZ)). InterPro: BNR repeat (IPR002860) Pfam: BNR repeat BNR repeats are short repeats never found closer than 40 residues together, which suggests that the repeat is structurally longer. These repeats are found in many glycosyl hydrolases as well as other extracellular proteins of unknown function. no singal peptide. 1 TMHs.
 
  
 0.882
azo2254
Conserved hypothetical secreted protein. Homology to PP2811 of P.putida of 32% (tremble:Q88J38). Has PF06980;Protein of unknown function (DUF1302)domain;IPR010727 This family contains a number of hypothetical bacterial proteins of unknown function that are approximately 600 residues long. Most family members seem to be from Pseudomonas. Signal peptide present. No TMH reported; Conserved hypothetical protein.
 
    0.740
azo1839
Probable transporter; Putative membrane protein MJ1562. TREMBL:Q88I00: 66% identity, 51% similarity The sterol-sensing domain (SSD) consists of approximately 180 amino acids organized into a cluster of five consecutive membrane-spanning domains and is found in proteins which have key roles in different aspects of cholesterol homeostasis or cholesterol-linked signalling such as sterol-regulated movement or the trafficking of specific cargoes. InterPro:IPR000731; SSD_5TM Found in :IPR003392: Patched family IPR004816: Hydroxymethylglutaryl-CoA reductase (NADPH Pfam:Patched:Patched family [...]
 
   
 0.730
azo2253
Probable exporter of RND superfamily; Putative membrane protein MJ1562. TREMBL:Q88J37: 52% identity, 66% similarity InterPro:IPR001036; Acrflvin_res. IPR000731; SSD_5TM Pfam:Patched:Patched family 2A067: efflux transporter putative Presence of signal peptide (Signal P predicted). Transmembrane helices 12 (TMHMM predicted); Family membership.
 
   
 0.730
azo0037
Probable exporter of RND superfamily; Putative membrane protein MJ1562. TREMBL:Q88LB6: 47% identity, 63% similarity InterPro:IPR000731; SSD_5TM InterPro: HMGCR/Patched 5TM box Pfam:Patched:Patched family 2A067: efflux transporter putative Signal peptide absent. Presence of 12 transmembrane helices; Family membership.
 
   
 0.729
azo1836
Hypothetical protein sharing 76% similarity(61% identity) with Hypothetical protein [Thauera aromatica]TrEMBl O87938. Has pfam06980, DUF1302 domain,Protein of unknown function (DUF1302). This family contains a number of hypothetical bacterial proteins of unknown function that are approximately 600 residues long. Most family members seem to be from Pseudomonas.(IPR010727) No Signal peptide or TMH being reported to be present; Function unclear.
 
    0.722
azo2252
Conserved hypothetical BNR domain protein. Homology to pa3080 of P. aeruginosa of 38% (trembl|Q9HZC8). InterPro: BNR repeat (IPR002860). Pfam: BNR repeat. BNR repeats are short repeats never found closer than 40 residues together, which suggests that the repeat is structurally longer. These repeats are found in many glycosyl hydrolases as well as other extracellular proteins of unknown function. singal peptide. no TMHs; Function unclear.
 
  
 0.714
azo1838
Conserved hypothetical BNR domain protein. Homology to pp3201 of P. putida of 46% (trembl|Q88I01). InterPro: BNR repeat (IPR002860). Pfam: BNR repeat. BNR repeats are short repeats never found closer than 40 residues together, which suggests that the repeat is structurally longer. These repeats are found in many glycosyl hydrolases as well as other extracellular proteins of unknown function. singal peptide. no TMHs; Function unclear.
 
  
 0.705
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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