Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo1970Conserved hypothetical protein. Homology to an orf of Rhizobium sp. NGR234 of 50% (tremblnew|AAQ87234(SRS)). No domain predicted. No signal peptide or TMH reported present. (177 aa)    
Predicted Functional Partners:
alsS
Acetolactate synthase large subunit (AHAS) (Acetohydroxy-acid synthase large subunit) (ALS). InterPro: Thiamine pyrophosphate dependent enzyme TIGRFAM: acolac_lg: acetolactate synthase large subunit; Family membership; Belongs to the TPP enzyme family.
 
     0.751
azo1971
Putative alcohol dehydrogenase; SPROT:ADH1_BACST:31% identity; 45% similarity Alcohol dehydrogenase (EC 1.1.1.1) (ADH-T). THERMOSTABLE NAD(+)-DEPENDENT ALCOHOL DEHYDROGENASE. an alcohol + nad(+) = an aldehyde or ketone + nadh. cofactor:binds 2 zinc ions per subunit (by similarity). InterPro: IPR002328; ADH_zinc. IPR002085:Adh_zn_family. Pfam:PF00107; ADH_zinc_N tdh: L-threonine 3-dehydrogenase; Specificity unclear.
       0.623
frlR
Putative GntR-family transcriptional regulator,; Family membership.
  
  
 0.590
pheA
Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity.
  
 
 0.547
metG
MetG protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
    
  0.543
ohpC
2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase; Hypothetical protein Rv2715/MT2788/Mb2734. TREMBL:Q9KH20: 58% identity, 73% similarity 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase; OhpC [Rhodococcus sp.] Catalysis of the reaction: 2-hydroxy-6-keto-nona-2,4-dienedioate + OH- = cis-2-hydroxypenta-2,4-dienoate + succinate. Pfam: alpha/ beta hydrolase; Ndr family; B12 binding domain. No signal peptide (Signal P predicted) or transmembrane helices (TMHMM predited) TIGRFAM: Co A. E activ TIGR00044: conserved hypothetical protein; Family membership.
 
  
  0.494
nagI
Gentisate 1,2-dioxygenase; Involved in catabolism of naphthalene via gentisate to fumarate and pyruvate. NagI is a gentisate 1,2-dioxygenase which converts gentisate to maleylpyruvate. Similar to TREMBL:O86041 (66% identity); TREMBL:Q8X655 (30% identity); TREMBL:Q8Y0F7 (33% identity); High confidence in function and specificity.
  
   
 0.482
mhpE
4-hydroxy 2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
       0.480
mhpF
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
       0.467
azo1944
Conserved hypothetical protein. Homology to mll3445) of M. loti of 71% (trembl|Q98G8). InterPro: Bacterial luciferase (IPR002103). Pfam: Luciferase-like monooxygenase. no signal peptide. no TMHS.
  
     0.446
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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