STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1987The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,; Specificity unclear. (419 aa)    
Predicted Functional Partners:
azo1986
Conserved hypothetical protein; Entry name TREMBL:Q89PQ1 Prim. accession # Q89PQ1 Identities = 241/381 (63%) Thiolase, N-terminal domain (Pfam predicted) Prediction: Non-secretory protein Signal peptide probability: 0.00 Number of predicted TMHs: 0.
 
 0.998
paaJ1
THIOLYTIC CLEAVAGE OF BETA-KETOADIPYL-COA TO SUCCINATE AND ACETYL-COA. Entry name:- TREMBL:Q84HH5 InterPro:- IPR002155; Thiolase. Pfam:- PF02803; Thiolase_C; 1. PF00108; Thiolase_N; 1. Identities = 298/398 (74%) Number of predicted TMHs: 0; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.970
fadAx
Probable acyl-CoA thiolase. Homology to fadAx of P. putida of 67% (gnl|keqq|ppu:PP2215(KEGG)). IPR002155; Thiolase. Pfam PF02803; Thiolase_C; 1. PF00108; Thiolase_N; 1. Two different types of thiolase are found both in eukaryotes and in prokaryotes: acetoacetyl-CoA thiolase (EC:2.3.1.9) and 3-ketoacyl-CoA thiolase (EC:2.3.1.16). 3-ketoacyl-CoA thiolase (also called thiolase I) has a broad chain-length specificity for its substrates and is involved in degradative pathways such as fatty acid -oxidation. Acetoacetyl-CoA thiolase (also called thiolase II) is specific for the thiolysis of a [...]
  
 0.970
fadA1
Probable 3-ketoacyl-CoA thiolase; Subunit of fatty acid oxidation complex, 3-keto-acyl-coa-thiolase. Activity:-acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA Entry name TREMBL:Q8G967 Prim. accession # Q8G967 Identities = 284/425 (66%) InterPro IPR002155; Thiolase. Pfam PF02803; Thiolase_C; 1. PF00108; Thiolase_N; 1. Number of predicted TMHs: 0 Prediction: Non-secretory protein Signal peptide probability: 0.000; Family membership; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.970
fadA2
Probable 3-ketoacyl-CoA thiolase; Activity:- acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA Entry name:- SWISSPROT:THIK_ECOLI Prim. accession # P21151 InterPro:- IPR002155; Thiolase. Pfam:-PF02803; Thiolase_C; 1. PF00108; Thiolase_N; 1. Identities = 177/400 (44%) Number of predicted TMHs: 0; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.970
thlA
Acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase):- catalytic activity:-2 acetyl-coa = coa + acetoacetyl-coa. Entry name SWISSPROT:THLA_CLOAB Prim. accession # P45359 Identities = 205/392 (52%) InterPro IPR002155; Thiolase. Pfam PF00108; thiolase; 1. Prediction: Non-secretory protein Signal peptide probability: 0.022 Number of predicted TMHs: 0; Family membership; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.970
paaJ2
Thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA (By similarity). Entry name PAAJ_ECOLI Primary accession number P77525 Identity: 150/410 (36%) InterPro IPR002155; Thiolase. Pfam PF02803; Thiolase_C; 1. Number of predicted TMHs: 0 Prediction: Non-secretory protein Signal peptide probability: 0.000; Family membership; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.970
azo3059
Probable 3-ketoadipyl-coa thiolase; Entry name TREMBL:Q84HH5 InterPro IPR002155; Thiolase. Pfam PF02803; Thiolase_C; 1. PF00108; Thiolase_N; 1. Identities = 309/402 (76%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.970
azo1985
Putative AMP-binding protein; Similar to TREMBL:Q89PS8 (59% identity). InterPro (IPR000873): AMP-dependent synthetase and ligase. Pfam (PF00501): AMP-binding enzyme; Function unclear.
 
  
 0.961
carBa2
Putative dioxygenase, hydroxylase small component; Hydroxylase large component of 1,2-dioxygenase protein complex, involved in aromatic compounds degradation. Putative 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase, CarBa. Involved in the aerobic degradation of carbazole by P.resinovorans sp. strain CA10. XlyX: Benzoate 12-dioxygenase alpha subunit (EC 1.14.12.10). DEGRADATION OF BENZOATE TO 2-HYDRO-12-DIHYDROXYBENZOATE (DHB). Benzoate 12-dioxygenase beta subunit (EC 1.14.12.10). DEGRADATION OF BENZOATE TO 2-HYDRO-12-DIHYDROXYBENZOATE (DHB). THE BETA SUBUNIT MAY BE RESPONSIBLE FOR THE SUBST [...]
 
     0.946
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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