STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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apbA2Putative 2-dehydropantoate 2-reductase (EC 1.1.1.169) (KPA reductase) (KPR). Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity). apbA_panE: 2-dehydropantoate 2-reductase; Specificity unclear. (336 aa)    
Predicted Functional Partners:
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
  
 0.740
azo1995
Conserved hypothetical protein; 41% Aldolase_II_N. Class II Aldolase and Adducin N-terminal domain Pfam: PF00596; Aldolase_II; 1. fucA: L-fuculose phosphate aldolase; High confidence in function and specificity.
 
     0.732
apbA1
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
     0.727
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 0.698
alkB
DNA-directed DNA polymerase; Alkylated DNA repair protein.Probably involved in the repair of alkylated DNA. Provides extensive resistance to alkylating agents.; High confidence in function and specificity.
   
    0.535
azo2783
DNA repair system specific for alkylated DNA; Probable RNA-directed RNA polymerase (EC 2.7.7.48) (RNA replicase) (216.5 kDa protein) (ORF1). alkb: alkylated DNA repair protein AlkB; Function unclear.
   
    0.535
azo1246
Conserved hypothetical mandelate racemase. Homology to bll6730 of B. japonicum of 76% (trembl|Q89FH0) Mandelate racemase and muconate lactonizing enzyme are two bacterial enzymes involved in aromatic acid catabolism. They catalyze mechanistically distinct reactions yet they are related at the level of their primary, quaternary (homooctamer) and tertiary structures. InterPro: Mandelate racemase/muconate lactonizing enzyme family (IPR001354) Pfam: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain; Specific [...]
  
    0.484
dehH
Hypothetical haloacetate dehalogenase H-1 (EC 3.8.1.3). Haloacetate + H(2)O = glycolate + halide TREMBL:Q8Y2S9: 58% identity, 67% similarity Gene name:dehH from Ralstonia solanacearum genome project. InterPro: Alpha/beta hydrolase fold InterPro:IPR000073; A/b_hydrolase. IPR000379: Ser_estrs. Pfam:PF00561; Abhydrolase_1 nadp_idh_euk: isocitrate dehydrogenase No TMH present absence of signal peptide; Family membership.
  
    0.427
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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