STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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apbA2Putative 2-dehydropantoate 2-reductase (EC 1.1.1.169) (KPA reductase) (KPR). Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity). apbA_panE: 2-dehydropantoate 2-reductase; Specificity unclear. (336 aa)    
Predicted Functional Partners:
azo1995
Conserved hypothetical protein; 41% Aldolase_II_N. Class II Aldolase and Adducin N-terminal domain Pfam: PF00596; Aldolase_II; 1. fucA: L-fuculose phosphate aldolase; High confidence in function and specificity.
 
     0.732
apbA1
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
     0.727
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
  
 0.711
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 0.664
alkB
DNA-directed DNA polymerase; Alkylated DNA repair protein.Probably involved in the repair of alkylated DNA. Provides extensive resistance to alkylating agents.; High confidence in function and specificity.
   
    0.503
azo2783
DNA repair system specific for alkylated DNA; Probable RNA-directed RNA polymerase (EC 2.7.7.48) (RNA replicase) (216.5 kDa protein) (ORF1). alkb: alkylated DNA repair protein AlkB; Function unclear.
   
    0.503
azo1246
Conserved hypothetical mandelate racemase. Homology to bll6730 of B. japonicum of 76% (trembl|Q89FH0) Mandelate racemase and muconate lactonizing enzyme are two bacterial enzymes involved in aromatic acid catabolism. They catalyze mechanistically distinct reactions yet they are related at the level of their primary, quaternary (homooctamer) and tertiary structures. InterPro: Mandelate racemase/muconate lactonizing enzyme family (IPR001354) Pfam: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain; Specific [...]
  
    0.447
dehH
Hypothetical haloacetate dehalogenase H-1 (EC 3.8.1.3). Haloacetate + H(2)O = glycolate + halide TREMBL:Q8Y2S9: 58% identity, 67% similarity Gene name:dehH from Ralstonia solanacearum genome project. InterPro: Alpha/beta hydrolase fold InterPro:IPR000073; A/b_hydrolase. IPR000379: Ser_estrs. Pfam:PF00561; Abhydrolase_1 nadp_idh_euk: isocitrate dehydrogenase No TMH present absence of signal peptide; Family membership.
  
    0.422
birA
biotin--[acetyl-CoA-carboxylase] ligase; BirA bifunctional protein [Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase (EC 6.3.4.15) (Biotin--protein ligase)]. birA acts both as a biotin-operon repressor and as the enzyme that synthesizes the corepressor, acetyl-coa:carbon- dioxide ligase. this protein also activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins. InterPro: Biotin--acetyl-CoA-carboxylase ligase birA_ligase: biotin--acetyl-CoA-carboxyla; Specificity unclear.
     
 0.406
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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