STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
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[Homology]
Score
acS1Acetyl-coenzyme A synthetase enables the cell to use acetate during aerobic growth to generate energy via the tca cycle, and biosynthetic compounds via the glyoxylate shunt. acetylates chey, the response regulator involved in flagellar movement and chemotaxis. Entry name SWISSPROT:ACSA_ECOLI Prim. accession # P27550 Identities = 145/546 (26%) Pfam PF00501; AMP-binding; 1. InterPro IPR000873; AMP-bind. Pfam PF00501; AMP-binding; 1. Number of predicted TMHs: 0; Family membership. (535 aa)    
Predicted Functional Partners:
abmA
2-amninobenzoyl-CoA monooxygenase/reductase (EC 1.14.13.40) Homology to abmA of A. evansii of 86% (trembl|Q93FB8(SRS). natural fusion protein of a monooxygenase and a reductase; contains flavin. Pfam: Monooxygnease; NADH:flavin oxidoreductase/NADH oxidorecutase. no signal peptide. no TMHs; High confidence in function and specificity.
 
 0.963
badR
Putative transcriptional activatory protein BadR (Benzoate anaerobic degradation regulator). Similar to SWISSPROT: sprot|BADR_RHOPA (25% Rhodopseudomonas palustris, transcriptional activatory protein BadR (benzoate anaerobic degradation regulator)) InterPro: IPR000835 HTH_MarR. Pfam: PF01047 MarR family; Family membership.
 
     0.867
pta
Conserved hypothetical phosphate acetyltransferase. Homology to pta of R. palustris of 63% (tremblnew|CAE30007). InterPro: Phosphate acetyl/butaryl transferase (IPR002505); MaoC-like dehydrogenase domain (IPR002539). Pfam: MaoC like domain; Phosphate acetyl/butaryl transferase. no signal peptide. no TMHs; Conserved hypothetical protein.
  
 
 0.845
abmC
Probable enoyl-CoA hydratase; Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O. Entry name TREMBL:Q93FB6 Identities = 224/280 (80%) Prim. accession # Q93FB6 InterPro IPR001753; EnCoA_hydrtse. Pfam PF00378; ECH; 1. Number of predicted TMHs: 0; High confidence in function and specificity; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 
 0.818
abmE
Conserved hypothetical protein. Homology to orf5 of Azoarcus evansii of 78% (tremble:Q93FB4). Pfam: Endoribonuclease L-PSP. Endoribonuclease active on single-stranded mRNA. Inhibits protein synthesis by cleavage of mRNA. Previously thought to inhibit protein synthesis initiation. This protein may also be involved in the regulation of purine biosynthesis. No signal peptide. No TMHs.
 
  
  0.785
pepM
Phosphoenolpyruvate phosphomutase precursor(Phosphoenolpyruvate mutase) (PEP mutase) (PEP phosphomutase).FORMATION OF A CARBON-PHOSPHORUS BOND BY CONVERTING PHOSPHOENOLPYRUVATE (PEP) TO PHOSPHONOPYRUVATE (P-PYR). 34% Isocit_lyase_ph; High confidence in function and specificity.
  
 
 0.773
azo1929
TREMBL:Q89PR6: 50% identity; 71% similarity Probable 4-hydroxybenzoyl-CoA thioesterase. InterPro:IPR008272; 4HBcoA_thiost_AS Pfam:4HBT:4-hydroxybenzoyl-CoA thioesterase TIGR00051: conserved hypothetical protein No transmembrane helices; Function unclear.
 
  
  0.762
abmD
Putative acyl-CoA dehydrogenase; Catalysis of the reaction:- acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor. Entry name TREMBL:Q98BT9 Prim. accession # Q98BT9 InterPro IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. Number of predicted TMHs: 0; Family membership.
  
 
 0.754
fadB1
Probable enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; Alpha-subunit of fatty acid oxidation complex. Entry name TREMBL:Q8G968 Prim. accession # Q8G968 Identities = 373/642 (58%) InterPro IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0 IPR008927; 6DGDH_C_like. IPR001753; EnCoA_hydrtse. Pfam PF00725; 3HCDH; 1. PF02737; 3HCDH_N; 1. PF00378; ECH; 1; Family membership.
  
 
 0.753
fadB2
Short-chain enoyl-CoA hydratase activity. Activity:- 3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O Entry name TREMBL:Q8P986 Prim. accession # Q8P986 InterPro IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. IPR008927; 6DGDH_C_like. IPR001753; EnCoA_hydrtse. IPR000205; NAD_BS. Pfam PF00725; 3HCDH; 1. PF02737; 3HCDH_N; 1. PF00378; ECH; 1. Identities = 468/796 (58%) Prediction: Signal peptide Signal peptide probability: 0.980 Number of predicted TMHs: 0; Family membership.
  
 
 0.753
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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