typA protein (Azoarcus sp. BH72) - STRING interaction network

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[Homology]

Score

typA

GTP-binding elongation factor,; High confidence in function and specificity. (605 aa)

Predicted Functional Partners:

guaA

0.782

rpsI

0.701

ychF

0.653

tsf

0.650

rplA

0.636

gltB

0.636

tig

0.632

rpmI

0.619

infC

0.607

abcZ

0.606

Your Current Organism:

Azoarcus sp. BH72

NCBI taxonomy Id: 62928
Other names: A. sp. BH72

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
abcZ	rplA	azo3185	azo3427	ABC transporter ATP-binding protein uup-1. InterPro: AAA ATPase superfamily Presence of SMC domain at N-terminal. Occurence of HypB/UreG nucleotide binding domain. FERM and yrdC domains are also present. Presence of uncharacterized P-loop hydralase domain. Presence of signal peptide and transmembrane helices. 61% identity and 76% similarity to Chromobacterium ABC transporter; Family membership.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.749
abcZ	rpmI	azo3185	azo1081	ABC transporter ATP-binding protein uup-1. InterPro: AAA ATPase superfamily Presence of SMC domain at N-terminal. Occurence of HypB/UreG nucleotide binding domain. FERM and yrdC domains are also present. Presence of uncharacterized P-loop hydralase domain. Presence of signal peptide and transmembrane helices. 61% identity and 76% similarity to Chromobacterium ABC transporter; Family membership.	50S ribosomal protein L35; Family membership; Belongs to the bacterial ribosomal protein bL35 family.	0.749
abcZ	rpsI	azo3185	azo2759	ABC transporter ATP-binding protein uup-1. InterPro: AAA ATPase superfamily Presence of SMC domain at N-terminal. Occurence of HypB/UreG nucleotide binding domain. FERM and yrdC domains are also present. Presence of uncharacterized P-loop hydralase domain. Presence of signal peptide and transmembrane helices. 61% identity and 76% similarity to Chromobacterium ABC transporter; Family membership.	30S ribosomal protein S9; High confidence in function and specificity; Belongs to the universal ribosomal protein uS9 family.	0.749
abcZ	typA	azo3185	azo1999	ABC transporter ATP-binding protein uup-1. InterPro: AAA ATPase superfamily Presence of SMC domain at N-terminal. Occurence of HypB/UreG nucleotide binding domain. FERM and yrdC domains are also present. Presence of uncharacterized P-loop hydralase domain. Presence of signal peptide and transmembrane helices. 61% identity and 76% similarity to Chromobacterium ABC transporter; Family membership.	GTP-binding elongation factor,; High confidence in function and specificity.	0.606
gltB	guaA	azo3642	azo1581	Ferredoxin-dependent glutamate synthase,; Specificity unclear.	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.925
gltB	typA	azo3642	azo1999	Ferredoxin-dependent glutamate synthase,; Specificity unclear.	GTP-binding elongation factor,; High confidence in function and specificity.	0.636
gltB	ychF	azo3642	azo0752	Ferredoxin-dependent glutamate synthase,; Specificity unclear.	Conserved hypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	0.492
guaA	gltB	azo1581	azo3642	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	Ferredoxin-dependent glutamate synthase,; Specificity unclear.	0.925
guaA	infC	azo1581	azo1080	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	0.523
guaA	rplA	azo1581	azo3427	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.945
guaA	rpmI	azo1581	azo1081	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	50S ribosomal protein L35; Family membership; Belongs to the bacterial ribosomal protein bL35 family.	0.554
guaA	rpsI	azo1581	azo2759	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	30S ribosomal protein S9; High confidence in function and specificity; Belongs to the universal ribosomal protein uS9 family.	0.648
guaA	tig	azo1581	azo2072	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.712
guaA	tsf	azo1581	azo1908	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	Elongation factor EF-Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.703
guaA	typA	azo1581	azo1999	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	GTP-binding elongation factor,; High confidence in function and specificity.	0.782
guaA	ychF	azo1581	azo0752	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	Conserved hypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	0.732
infC	guaA	azo1080	azo1581	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.	0.523
infC	rplA	azo1080	azo3427	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.934
infC	rpmI	azo1080	azo1081	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	50S ribosomal protein L35; Family membership; Belongs to the bacterial ribosomal protein bL35 family.	0.972
infC	rpsI	azo1080	azo2759	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	30S ribosomal protein S9; High confidence in function and specificity; Belongs to the universal ribosomal protein uS9 family.	0.955