Type 4 pilus biogenesis protein; Pilus assembly protein PilC is a component of the pilus biogenesis apparatus, similarity to pir|B35384 (50%). This apparatus is responsible for the stabilization, translocation and assembly of the monomeric pilin subunits into the pilus organelle. InterPro (IPR001992): Bacterial type II secretion system protein. InterPro (IPR003004): Bacterial general secretion pathway protein F Pfam (PF00482): Bacterial type II secretion system protein TMHMM reporting three TMH; High confidence in function and specificity.

General secretion pathway protein F; Type II secretory pathway component F,; Specificity unclear.

General secretion pathway protein F,similar trembl|Q88HD6 (39%). The general (type II) secretion pathway (GSP) within Gram-negative bacteria is a signal sequence-dependent process responsible for protein export. The process has two stages: exoproteins are first translocated across the inner membrane by the general signal-dependent export pathway (GEP), and then across the outer membrane by a species-specific accessory mechanism. InterPro (IPR001992): Bacterial type II secretion system protein. InterPro (IPR003004): Bacterial general secretion pathway protein F Pfam (PF00482): Bacterial [...]

Type 4 fimbrial biogenesis protein PilM, similarity to trembl|Q82SK1 (56%)and to pir|S77726 (47%). Four genes,pilM-P, encode the necessary proteins and pilM is required for the assembly of the type IV fimbriae in Pseudomonas aeruginosa; Specificity unclear.

Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.

Site-specific DNA-methyltransferase (adenine-specific); Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.

2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase. Homology to dapD of E. coli of 74% (sprot|DAPD_ECOLI). Involved in biosynthesis of diaminopimelate and lysine from aspartate semialdehyde. Catalytic activity: succinyl-coa + (r)-2,3,4,5-tetrahydropyridine- 2,6-dicarboxylate + h(2)o = coa + (r)-2-(succinylamino)-6- oxoheptanedioate. InterPro: Bacterial transferase hexapeptide repeat (IPR001451) no signal peptide no TMH; High confidence in function and specificity.

N-succinyldiaminopimelate aminotransferase, DapC converting N-succinyl-2-amino-6-ketopimelate, the product of the succinylase DapD, to N-succinyl-L,L-DAP, the substrate of the desuccinylase DapE. Similar to trembl|Q8XZK1 (63%) and to pir|F83189 (57%). Pfam: Aminotransferase, class I and II; Specificity unclear.

Type 4 fimbrial biogenesis protein PilQ, similarity to sprot|PILQ_PSEAE (41%) and trembl|Q8XV60 (45%). PilQ is essential for the biogenesis of type IV pili. Its precise function is unknown, but it has been suggested that it may act as a pilus channel in the final stages of pilus assembly. InterPro (PF00263): General (type II) secretion pathway (GSP) D protein SignalP reporting signal peptide; Specificity unclear.