node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
azo2010 | azo2018 | azo2010 | azo2018 | Conserved hypothetical protein. Homology to CV1087 of C.violaceum of 69% (trembl:Q7NZ35). Has PF04384; Protein of unknown function (DUF528);IPR007479: Small bacterial protein of unknown function. No signal peptide or TMH present. | RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic [...] | 0.680 |
azo2010 | dnaK | azo2010 | azo1063 | Conserved hypothetical protein. Homology to CV1087 of C.violaceum of 69% (trembl:Q7NZ35). Has PF04384; Protein of unknown function (DUF528);IPR007479: Small bacterial protein of unknown function. No signal peptide or TMH present. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.465 |
azo2010 | fdx2 | azo2010 | azo2011 | Conserved hypothetical protein. Homology to CV1087 of C.violaceum of 69% (trembl:Q7NZ35). Has PF04384; Protein of unknown function (DUF528);IPR007479: Small bacterial protein of unknown function. No signal peptide or TMH present. | Fdx2 protein; Ferredoxin 2Fe-2S. Homology to fdx of E. coli of 70% (sprot|FER_ECOLI). Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. Although the function of this ferredoxin is unknown it is probable that it has a role as a cellular electron transfer protein. Involved in the in vivo assembly of the Fe-S clusters in a wide variety of iron- sulfur proteins. InterPro: Ferredoxin (IPR001055); Adrenodoxin (IPR001055) Pfam: 2Fe-2S iorn-sulfur cluster binding domain no signal peptide no TMHs; High confidence in function and specificity. | 0.993 |
azo2010 | hscA | azo2010 | azo2012 | Conserved hypothetical protein. Homology to CV1087 of C.violaceum of 69% (trembl:Q7NZ35). Has PF04384; Protein of unknown function (DUF528);IPR007479: Small bacterial protein of unknown function. No signal peptide or TMH present. | Probable chaperone protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.964 |
azo2010 | hscB | azo2010 | azo2013 | Conserved hypothetical protein. Homology to CV1087 of C.violaceum of 69% (trembl:Q7NZ35). Has PF04384; Protein of unknown function (DUF528);IPR007479: Small bacterial protein of unknown function. No signal peptide or TMH present. | Putative co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.985 |
azo2010 | iscS1 | azo2010 | azo2016 | Conserved hypothetical protein. Homology to CV1087 of C.violaceum of 69% (trembl:Q7NZ35). Has PF04384; Protein of unknown function (DUF528);IPR007479: Small bacterial protein of unknown function. No signal peptide or TMH present. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.878 |
azo2010 | iscU | azo2010 | azo2015 | Conserved hypothetical protein. Homology to CV1087 of C.violaceum of 69% (trembl:Q7NZ35). Has PF04384; Protein of unknown function (DUF528);IPR007479: Small bacterial protein of unknown function. No signal peptide or TMH present. | NifU-related protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.968 |
azo2010 | nifQ | azo2010 | azo0529 | Conserved hypothetical protein. Homology to CV1087 of C.violaceum of 69% (trembl:Q7NZ35). Has PF04384; Protein of unknown function (DUF528);IPR007479: Small bacterial protein of unknown function. No signal peptide or TMH present. | Putative NifQ protein. Homology to nifQ of A. vinelandii of 33% (sprot|NIFQ_AZOVI(SRS) NifQ is involved in early stages of the biosynthesis of the iron-molybdenum cofactor (FeMo-co), which is an integral part of the active site of dinitrogenase [2]. The conserved C-terminal cysteine residues may be involved in metal binding. Pfam: NifQ no signal peptide no TMHs; Family membership. | 0.631 |
azo2010 | nifU | azo2010 | azo0553 | Conserved hypothetical protein. Homology to CV1087 of C.violaceum of 69% (trembl:Q7NZ35). Has PF04384; Protein of unknown function (DUF528);IPR007479: Small bacterial protein of unknown function. No signal peptide or TMH present. | Probable nitrogen fixation protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. | 0.855 |
azo2010 | yfhF | azo2010 | azo2014 | Conserved hypothetical protein. Homology to CV1087 of C.violaceum of 69% (trembl:Q7NZ35). Has PF04384; Protein of unknown function (DUF528);IPR007479: Small bacterial protein of unknown function. No signal peptide or TMH present. | Putative regulatory Protein yfhF, 72% identity (82% similarity) to TrEMBL;P36539 of E.coli. Has PF01521, HesB-like domain;(IPR000361, HesB_yadR_yfhF); This family includes HesB which may be involved in nitrogen fixation; the hesB gene is expressed only under nitrogen fixation conditions. Other members of this family include various hypothetical proteins of which P46847 and NP31774 also contains NifU-like domains NifU which is also involved in nitrogen fixation. In the gram-negative soil bacterium Rhizobium etli, the hesB-like gene iscN is required for nitrogen fixation; High confidence [...] | 0.928 |
azo2018 | azo2010 | azo2018 | azo2010 | RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic [...] | Conserved hypothetical protein. Homology to CV1087 of C.violaceum of 69% (trembl:Q7NZ35). Has PF04384; Protein of unknown function (DUF528);IPR007479: Small bacterial protein of unknown function. No signal peptide or TMH present. | 0.680 |
azo2018 | fdx2 | azo2018 | azo2011 | RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic [...] | Fdx2 protein; Ferredoxin 2Fe-2S. Homology to fdx of E. coli of 70% (sprot|FER_ECOLI). Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. Although the function of this ferredoxin is unknown it is probable that it has a role as a cellular electron transfer protein. Involved in the in vivo assembly of the Fe-S clusters in a wide variety of iron- sulfur proteins. InterPro: Ferredoxin (IPR001055); Adrenodoxin (IPR001055) Pfam: 2Fe-2S iorn-sulfur cluster binding domain no signal peptide no TMHs; High confidence in function and specificity. | 0.726 |
azo2018 | hscA | azo2018 | azo2012 | RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic [...] | Probable chaperone protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.663 |
azo2018 | hscB | azo2018 | azo2013 | RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic [...] | Putative co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.955 |
azo2018 | iscS1 | azo2018 | azo2016 | RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic [...] | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.949 |
azo2018 | iscU | azo2018 | azo2015 | RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic [...] | NifU-related protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.970 |
azo2018 | nifQ | azo2018 | azo0529 | RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic [...] | Putative NifQ protein. Homology to nifQ of A. vinelandii of 33% (sprot|NIFQ_AZOVI(SRS) NifQ is involved in early stages of the biosynthesis of the iron-molybdenum cofactor (FeMo-co), which is an integral part of the active site of dinitrogenase [2]. The conserved C-terminal cysteine residues may be involved in metal binding. Pfam: NifQ no signal peptide no TMHs; Family membership. | 0.449 |
azo2018 | nifU | azo2018 | azo0553 | RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic [...] | Probable nitrogen fixation protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. | 0.826 |
azo2018 | yfhF | azo2018 | azo2014 | RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic [...] | Putative regulatory Protein yfhF, 72% identity (82% similarity) to TrEMBL;P36539 of E.coli. Has PF01521, HesB-like domain;(IPR000361, HesB_yadR_yfhF); This family includes HesB which may be involved in nitrogen fixation; the hesB gene is expressed only under nitrogen fixation conditions. Other members of this family include various hypothetical proteins of which P46847 and NP31774 also contains NifU-like domains NifU which is also involved in nitrogen fixation. In the gram-negative soil bacterium Rhizobium etli, the hesB-like gene iscN is required for nitrogen fixation; High confidence [...] | 0.891 |
dnaK | azo2010 | azo1063 | azo2010 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Conserved hypothetical protein. Homology to CV1087 of C.violaceum of 69% (trembl:Q7NZ35). Has PF04384; Protein of unknown function (DUF528);IPR007479: Small bacterial protein of unknown function. No signal peptide or TMH present. | 0.465 |