| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo2018 | fdx2 | azo2018 | azo2011 | RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic [...] | Fdx2 protein; Ferredoxin 2Fe-2S. Homology to fdx of E. coli of 70% (sprot|FER_ECOLI). Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. Although the function of this ferredoxin is unknown it is probable that it has a role as a cellular electron transfer protein. Involved in the in vivo assembly of the Fe-S clusters in a wide variety of iron- sulfur proteins. InterPro: Ferredoxin (IPR001055); Adrenodoxin (IPR001055) Pfam: 2Fe-2S iorn-sulfur cluster binding domain no signal peptide no TMHs; High confidence in function and specificity. | 0.726 |
| azo2018 | hscA | azo2018 | azo2012 | RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic [...] | Probable chaperone protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.663 |
| azo2018 | hscB | azo2018 | azo2013 | RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic [...] | Putative co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.955 |
| azo2018 | iscS1 | azo2018 | azo2016 | RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic [...] | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.949 |
| azo2018 | iscS2 | azo2018 | azo2017 | RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic [...] | Probable cysteine desulfurase (NifS protein homolog). Homology to iscS of M. thermophila of 40% (sprot|ISCS_METTE) Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). InterPro: Aminotransferase class-V (IPR000192) Pfam: aminotransferase class-V no signal peptide no TMHs ahpD: alkylhydroperoxidase AhpD; Family membership. | 0.969 |
| azo2018 | iscU | azo2018 | azo2015 | RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic [...] | NifU-related protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.970 |
| azo2018 | nifS | azo2018 | azo0552 | RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic [...] | Cysteine desulphurase; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. | 0.855 |
| azo2018 | yfhF | azo2018 | azo2014 | RrF2 family protein. These are small proteins of 12 to 18 kD which seem to contain a signal sequence, and may represent a family of probable transcriptional regulators. Similar to SWISSPROT: sprot|YOR2_AZOVI (50% Azotobacter vinelandii, hypothetical upf0074 protein) / TREMBL: trembl|Q8Y0M5 (72% Ralstonia solanacearum (Pseudomonas solanacearum), hypothetical protein rsc1018) Pfam: PF02082 Transcriptional regulator. TIGRFAM: TIGR00738 rrf2 family protein (Uncharacterized protein family UPF0074 / putative transcriptional regulator). Signal P reporting signal peptide. HTH reporting nucleic [...] | Putative regulatory Protein yfhF, 72% identity (82% similarity) to TrEMBL;P36539 of E.coli. Has PF01521, HesB-like domain;(IPR000361, HesB_yadR_yfhF); This family includes HesB which may be involved in nitrogen fixation; the hesB gene is expressed only under nitrogen fixation conditions. Other members of this family include various hypothetical proteins of which P46847 and NP31774 also contains NifU-like domains NifU which is also involved in nitrogen fixation. In the gram-negative soil bacterium Rhizobium etli, the hesB-like gene iscN is required for nitrogen fixation; High confidence [...] | 0.891 |
| csdB | iscS1 | azo0369 | azo2016 | Cysteine desulphurases required for the mobilization of sulphur from cysteine. They are present in all organisms, where they are involved in iron-sulphur (Fe-S) cluster biosynthesis. Similar to sprot|CSD1_MYCLE (54%), to trembl|Q82WT8 (55%) and to tremblnew|BAB21542 (34%). Pfam (PF00266): Aminotransferase class-V Pfam (PF01041): DegT/DnrJ/EryC1/StrS aminotransferase family; Function unclear. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.713 |
| csdB | iscS2 | azo0369 | azo2017 | Cysteine desulphurases required for the mobilization of sulphur from cysteine. They are present in all organisms, where they are involved in iron-sulphur (Fe-S) cluster biosynthesis. Similar to sprot|CSD1_MYCLE (54%), to trembl|Q82WT8 (55%) and to tremblnew|BAB21542 (34%). Pfam (PF00266): Aminotransferase class-V Pfam (PF01041): DegT/DnrJ/EryC1/StrS aminotransferase family; Function unclear. | Probable cysteine desulfurase (NifS protein homolog). Homology to iscS of M. thermophila of 40% (sprot|ISCS_METTE) Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). InterPro: Aminotransferase class-V (IPR000192) Pfam: aminotransferase class-V no signal peptide no TMHs ahpD: alkylhydroperoxidase AhpD; Family membership. | 0.713 |
| csdB | iscU | azo0369 | azo2015 | Cysteine desulphurases required for the mobilization of sulphur from cysteine. They are present in all organisms, where they are involved in iron-sulphur (Fe-S) cluster biosynthesis. Similar to sprot|CSD1_MYCLE (54%), to trembl|Q82WT8 (55%) and to tremblnew|BAB21542 (34%). Pfam (PF00266): Aminotransferase class-V Pfam (PF01041): DegT/DnrJ/EryC1/StrS aminotransferase family; Function unclear. | NifU-related protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.988 |
| csdB | nifS | azo0369 | azo0552 | Cysteine desulphurases required for the mobilization of sulphur from cysteine. They are present in all organisms, where they are involved in iron-sulphur (Fe-S) cluster biosynthesis. Similar to sprot|CSD1_MYCLE (54%), to trembl|Q82WT8 (55%) and to tremblnew|BAB21542 (34%). Pfam (PF00266): Aminotransferase class-V Pfam (PF01041): DegT/DnrJ/EryC1/StrS aminotransferase family; Function unclear. | Cysteine desulphurase; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. | 0.713 |
| csdB | yfhF | azo0369 | azo2014 | Cysteine desulphurases required for the mobilization of sulphur from cysteine. They are present in all organisms, where they are involved in iron-sulphur (Fe-S) cluster biosynthesis. Similar to sprot|CSD1_MYCLE (54%), to trembl|Q82WT8 (55%) and to tremblnew|BAB21542 (34%). Pfam (PF00266): Aminotransferase class-V Pfam (PF01041): DegT/DnrJ/EryC1/StrS aminotransferase family; Function unclear. | Putative regulatory Protein yfhF, 72% identity (82% similarity) to TrEMBL;P36539 of E.coli. Has PF01521, HesB-like domain;(IPR000361, HesB_yadR_yfhF); This family includes HesB which may be involved in nitrogen fixation; the hesB gene is expressed only under nitrogen fixation conditions. Other members of this family include various hypothetical proteins of which P46847 and NP31774 also contains NifU-like domains NifU which is also involved in nitrogen fixation. In the gram-negative soil bacterium Rhizobium etli, the hesB-like gene iscN is required for nitrogen fixation; High confidence [...] | 0.505 |
| cyaY | fdx2 | azo3652 | azo2011 | Putative CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | Fdx2 protein; Ferredoxin 2Fe-2S. Homology to fdx of E. coli of 70% (sprot|FER_ECOLI). Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. Although the function of this ferredoxin is unknown it is probable that it has a role as a cellular electron transfer protein. Involved in the in vivo assembly of the Fe-S clusters in a wide variety of iron- sulfur proteins. InterPro: Ferredoxin (IPR001055); Adrenodoxin (IPR001055) Pfam: 2Fe-2S iorn-sulfur cluster binding domain no signal peptide no TMHs; High confidence in function and specificity. | 0.892 |
| cyaY | hscA | azo3652 | azo2012 | Putative CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | Probable chaperone protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.711 |
| cyaY | hscB | azo3652 | azo2013 | Putative CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | Putative co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.878 |
| cyaY | iscS1 | azo3652 | azo2016 | Putative CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.967 |
| cyaY | iscS2 | azo3652 | azo2017 | Putative CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | Probable cysteine desulfurase (NifS protein homolog). Homology to iscS of M. thermophila of 40% (sprot|ISCS_METTE) Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). InterPro: Aminotransferase class-V (IPR000192) Pfam: aminotransferase class-V no signal peptide no TMHs ahpD: alkylhydroperoxidase AhpD; Family membership. | 0.958 |
| cyaY | iscU | azo3652 | azo2015 | Putative CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | NifU-related protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.983 |
| cyaY | nifS | azo3652 | azo0552 | Putative CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | Cysteine desulphurase; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. | 0.958 |