STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysEProbable serine acetyltransferase (EC 2.3.1.30). Homology to cysE of B. subtilis of 48% (sprot|CYSE_BACSU). no signal peptide no TMHs; Family membership. (251 aa)    
Predicted Functional Partners:
cysM
Cysteine synthase chloroplast precursor,; High confidence in function and specificity; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.996
cysK
Cysteine synthase A,; High confidence in function and specificity; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.986
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.913
cysS
CysS protein; Cysteinyl-tRNA synthetase (EC 6.1.1.16) (Cysteine--tRNA ligase) (CysRS). InterPro: Cysteinyl-tRNA synthetase cysS: cysteinyl-tRNA synthetase; High confidence in function and specificity; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.908
hom
Homoserine dehydrogenase catalyzes NAD-dependent reduction of aspartate beta-semialdehyde into homoserine. This reaction is the third step in a pathway leading from aspartate to homoserine. Similar to TREMBL:Q9RAM9 (77%) and to pir|DEPSHA(PIR (Georgetown University) (56%). Pfam: Homoserine dehydrogenase; High confidence in function and specificity.
     
 0.905
pssA
This enzyme, CDP-diacylglycerol--serine O-phosphatidyltransferase, is involved in phospholipid biosynthesis catalyzing the reaction CDP-diacylglycerol + L-serine = CMP + L-1-phosphatidylserine. Entry name:-SWISSPROT:PSS_HELPY identity:- 34% InterPro:-IPR000462; CDP-OH_P_trans. IPR004533; PssA. Pfam:- PF01066; CDP-OH_P_transf; 1. Number of predicted TMHs: 6 Prediction: Non-secretory protein Signal peptide probability: 0.047(YES); Family membership; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
  0.903
gumD
Putative glycosyltransferase; 43% Bact_transf. Pfam:PF02397; Bac_transf; 1. TMhelix:5; Specificity unclear.
  
 
 0.792
azo3193
Glycosyltransferase; Might transfer a sugar moiety directly to a lipd acceptor. Putative colanic biosynthesis UDP-glucose lipid carrier transferase. InterPro: Bacterial sugar transferase; Family membership.
  
 
 0.792
serB
Phosphoserine phosphatase, SerB, catalyzes the final step in serine biosynthesis in E. coli. It hydrolyses the phosphate group from phosphoserine to yield serine. Similar to trembl|Q82X56 (54%) and to sprot|SERB_ECOLI (37%). TIGRFAM: phosphoserine phosphatase SerB Pfam (PF00702): haloacid dehalogenase-like hydrolase; Specificity unclear.
    
 0.679
nadA
Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
  
    0.669
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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