| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acnA | azo2049 | azo1533 | azo2049 | Probable aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Conserved hypothetical protein. Homology to BTH_I1915 of Burkholderia thailandensis of 45%. Pfam: Prophage CP4-57 regulatory protein (AlpA)., This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppress two phenotypes of a delta lon protease mutant,overproduction of capsular polysaccharide and sensitivity to UV light. Several of the sequences in this family are thought to be DNA-binding proteins. No signal peptide. No TMHs. | 0.573 |
| acnA | fumB | azo1533 | azo2415 | Probable aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.744 |
| acnA | gltA | azo1533 | azo1554 | Probable aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Probable citrate synthase. Homology to gltA of s. meliloti of 69% (sprot|CISY_RHIME). Citrate synthase is a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs' cycle: Citrate + CoA = acetyl-CoA + H2 O + oxaloacetate InterPro: Citrate synthase (IPR002020) Pfam: Citrate synthase no signal peptide no TMHs; High confidence in function and specificity. | 0.999 |
| acnA | gltB | azo1533 | azo3642 | Probable aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | 0.663 |
| acnA | maeB1 | azo1533 | azo0821 | Probable aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Probable malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) (EC 1.1.1.40) (NADP-ME). Homology to dme of S. meliloti of 60% (sprot|MAO1_RHIME). Required for symbiotic nitrogen fixation. Plays a key role in the conversion of malate to acetyl-CoA for efficient tricarboxylic acid cycle function in nitrogen-fixating bacteria. Tigrfam: pta: phosphotransacetylase Pfam: Malic enzyme; Phosphate acetyl/butaryltransferase no signal peptide no TMHs; High confidence in function and specificity. | 0.684 |
| acnA | maeB2 | azo1533 | azo3211 | Probable aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Probable malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+). Homology to dme of S. meliloti of 61% (sprot|MAO1_RHIME). Required for symbiotic nitrogen fixation. Plays a key role in the conversion of malate to acetyl-CoA for efficient tricarboxylic acid cycle function in nitrogen-fixating bacteria. InterPro: Phosphate acetyl/butaryl transferase (IPR002505); Malic enzyme (IPR001891) Pfam: Malic enzyme; Phosphate acetyl/butaryl transferase Tigrfam: pta: phosphotransacetylase no signal peptide no TMHs; High confidence in function and specificity. | 0.684 |
| acnA | mdh | azo1533 | azo1547 | Probable aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.945 |
| acnA | pta | azo1533 | azo3638 | Probable aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Conserved hypothetical phosphate acetyltransferase. Homology to pta of R. palustris of 63% (tremblnew|CAE30007). InterPro: Phosphate acetyl/butaryl transferase (IPR002505); MaoC-like dehydrogenase domain (IPR002539). Pfam: MaoC like domain; Phosphate acetyl/butaryl transferase. no signal peptide. no TMHs; Conserved hypothetical protein. | 0.457 |
| azo2049 | acnA | azo2049 | azo1533 | Conserved hypothetical protein. Homology to BTH_I1915 of Burkholderia thailandensis of 45%. Pfam: Prophage CP4-57 regulatory protein (AlpA)., This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppress two phenotypes of a delta lon protease mutant,overproduction of capsular polysaccharide and sensitivity to UV light. Several of the sequences in this family are thought to be DNA-binding proteins. No signal peptide. No TMHs. | Probable aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.573 |
| azo2049 | fumB | azo2049 | azo2415 | Conserved hypothetical protein. Homology to BTH_I1915 of Burkholderia thailandensis of 45%. Pfam: Prophage CP4-57 regulatory protein (AlpA)., This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppress two phenotypes of a delta lon protease mutant,overproduction of capsular polysaccharide and sensitivity to UV light. Several of the sequences in this family are thought to be DNA-binding proteins. No signal peptide. No TMHs. | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.871 |
| azo2049 | gltA | azo2049 | azo1554 | Conserved hypothetical protein. Homology to BTH_I1915 of Burkholderia thailandensis of 45%. Pfam: Prophage CP4-57 regulatory protein (AlpA)., This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppress two phenotypes of a delta lon protease mutant,overproduction of capsular polysaccharide and sensitivity to UV light. Several of the sequences in this family are thought to be DNA-binding proteins. No signal peptide. No TMHs. | Probable citrate synthase. Homology to gltA of s. meliloti of 69% (sprot|CISY_RHIME). Citrate synthase is a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs' cycle: Citrate + CoA = acetyl-CoA + H2 O + oxaloacetate InterPro: Citrate synthase (IPR002020) Pfam: Citrate synthase no signal peptide no TMHs; High confidence in function and specificity. | 0.513 |
| azo2049 | gltB | azo2049 | azo3642 | Conserved hypothetical protein. Homology to BTH_I1915 of Burkholderia thailandensis of 45%. Pfam: Prophage CP4-57 regulatory protein (AlpA)., This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppress two phenotypes of a delta lon protease mutant,overproduction of capsular polysaccharide and sensitivity to UV light. Several of the sequences in this family are thought to be DNA-binding proteins. No signal peptide. No TMHs. | Ferredoxin-dependent glutamate synthase,; Specificity unclear. | 0.896 |
| azo2049 | icmF | azo2049 | azo0696 | Conserved hypothetical protein. Homology to BTH_I1915 of Burkholderia thailandensis of 45%. Pfam: Prophage CP4-57 regulatory protein (AlpA)., This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppress two phenotypes of a delta lon protease mutant,overproduction of capsular polysaccharide and sensitivity to UV light. Several of the sequences in this family are thought to be DNA-binding proteins. No signal peptide. No TMHs. | Probable methylmalonyl-coa mutase protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.754 |
| azo2049 | maeB1 | azo2049 | azo0821 | Conserved hypothetical protein. Homology to BTH_I1915 of Burkholderia thailandensis of 45%. Pfam: Prophage CP4-57 regulatory protein (AlpA)., This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppress two phenotypes of a delta lon protease mutant,overproduction of capsular polysaccharide and sensitivity to UV light. Several of the sequences in this family are thought to be DNA-binding proteins. No signal peptide. No TMHs. | Probable malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) (EC 1.1.1.40) (NADP-ME). Homology to dme of S. meliloti of 60% (sprot|MAO1_RHIME). Required for symbiotic nitrogen fixation. Plays a key role in the conversion of malate to acetyl-CoA for efficient tricarboxylic acid cycle function in nitrogen-fixating bacteria. Tigrfam: pta: phosphotransacetylase Pfam: Malic enzyme; Phosphate acetyl/butaryltransferase no signal peptide no TMHs; High confidence in function and specificity. | 0.598 |
| azo2049 | maeB2 | azo2049 | azo3211 | Conserved hypothetical protein. Homology to BTH_I1915 of Burkholderia thailandensis of 45%. Pfam: Prophage CP4-57 regulatory protein (AlpA)., This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppress two phenotypes of a delta lon protease mutant,overproduction of capsular polysaccharide and sensitivity to UV light. Several of the sequences in this family are thought to be DNA-binding proteins. No signal peptide. No TMHs. | Probable malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+). Homology to dme of S. meliloti of 61% (sprot|MAO1_RHIME). Required for symbiotic nitrogen fixation. Plays a key role in the conversion of malate to acetyl-CoA for efficient tricarboxylic acid cycle function in nitrogen-fixating bacteria. InterPro: Phosphate acetyl/butaryl transferase (IPR002505); Malic enzyme (IPR001891) Pfam: Malic enzyme; Phosphate acetyl/butaryl transferase Tigrfam: pta: phosphotransacetylase no signal peptide no TMHs; High confidence in function and specificity. | 0.598 |
| azo2049 | mdh | azo2049 | azo1547 | Conserved hypothetical protein. Homology to BTH_I1915 of Burkholderia thailandensis of 45%. Pfam: Prophage CP4-57 regulatory protein (AlpA)., This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppress two phenotypes of a delta lon protease mutant,overproduction of capsular polysaccharide and sensitivity to UV light. Several of the sequences in this family are thought to be DNA-binding proteins. No signal peptide. No TMHs. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.576 |
| azo2049 | mutB | azo2049 | azo0685 | Conserved hypothetical protein. Homology to BTH_I1915 of Burkholderia thailandensis of 45%. Pfam: Prophage CP4-57 regulatory protein (AlpA)., This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppress two phenotypes of a delta lon protease mutant,overproduction of capsular polysaccharide and sensitivity to UV light. Several of the sequences in this family are thought to be DNA-binding proteins. No signal peptide. No TMHs. | Probable Methylmalonyl-CoA mutase large subunit; FUNCTION: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates (By similarity). ACtivity:- (R)-2-Methylmalonyl-CoA = succinyl-CoA Entry name :- MUTB_PORGI Primary accession number :-Q59677 Identities = 467/679 (68%) InterPro :-IPR006159; Acid_CoA_mut_C. IPR006158; B12-binding. IPR006099; MMCoA_mutase. IPR006098; MMCoA_mutase_N. IPR006100; MMCoA_mutase_sub. Pfam PF02310; B12-binding; 1. PF01642; MM_CoA_mutase; 1. Prediction: Non-secretory protein Signal [...] | 0.754 |
| azo2049 | pta | azo2049 | azo3638 | Conserved hypothetical protein. Homology to BTH_I1915 of Burkholderia thailandensis of 45%. Pfam: Prophage CP4-57 regulatory protein (AlpA)., This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppress two phenotypes of a delta lon protease mutant,overproduction of capsular polysaccharide and sensitivity to UV light. Several of the sequences in this family are thought to be DNA-binding proteins. No signal peptide. No TMHs. | Conserved hypothetical phosphate acetyltransferase. Homology to pta of R. palustris of 63% (tremblnew|CAE30007). InterPro: Phosphate acetyl/butaryl transferase (IPR002505); MaoC-like dehydrogenase domain (IPR002539). Pfam: MaoC like domain; Phosphate acetyl/butaryl transferase. no signal peptide. no TMHs; Conserved hypothetical protein. | 0.557 |
| fumB | acnA | azo2415 | azo1533 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Probable aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.744 |
| fumB | azo2049 | azo2415 | azo2049 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Conserved hypothetical protein. Homology to BTH_I1915 of Burkholderia thailandensis of 45%. Pfam: Prophage CP4-57 regulatory protein (AlpA)., This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppress two phenotypes of a delta lon protease mutant,overproduction of capsular polysaccharide and sensitivity to UV light. Several of the sequences in this family are thought to be DNA-binding proteins. No signal peptide. No TMHs. | 0.871 |
