Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dppFHypothetical ABC transporter ATP-binding protein yliA. PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM YLIABCD. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. TREMBL:Q82S74: 52% identity, 64% similarity. InterPro: IPR003593; AAA_ATPase. No signal peptide No transmembrane helices. IPR003439; ABC_transporter. IPR010066; Oligo_HPY. Pfam:PF00005; ABC_tran; 2. ProDom: PD000006; ABC_transporter; 1. SMART:SM00382; AAA; 2. TIGRFAMs TIGR01727; oligo_HPY mobB: molybdopterin-guanine dinucleotid; High confidence in function and specificity. (666 aa)    
Predicted Functional Partners:
appB
Putative Oligopeptide ABC transporter, permease protein; Dipeptide transport system permease protein dppB. Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. InterPro: Binding-protein-dependent transport systems inner membrane component crcB: crcB protein; High confidence in function and specificity.
 
 0.996
appC
Oligopeptide transport system permease protein appC. This protein is a component of an oligopeptide permease a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence though unlike OPP is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity). pts-Glc: PTS system maltose and gluco; High confidence in function and specificity.
 0.996
dppC
ABC transporter, permease protein; Part of the ABC transporter complex dppABCD involved in dipeptide import. Probably responsible for the translocation of the substrate across the membrane. Similar to the dipeptide permease protein, DppC in E.coli; Specificity unclear.
 0.995
dppB
Putative dipeptide transport system, permease protein; Part of the ABC transporter complex dppABCD involved in dipeptide import. Probably responsible for the translocation of the substrate across the membrane. Similar to the dipeptide permease protein, DppB in E.coli; Specificity unclear.
 
 0.986
azo1571
Conserved hypothetical protein. Homology to hbpA of N. europaea of 56%. Protein consist of two domains: 1. bacterial extracellular sloute protein with homology to heme-binding protein A which is important for the heme aquisition and 2. a transmembrane helix a the C-terminus (unusual combination). Interpro: Bacterial extracellular solute-binding protein, family 5 (IPR000914) Pfam: Bacterial extracellular solute binding protein Signal peptide one TMH.
 
 0.981
azo1044
Conserved hypothetical membrane protein. Homology to ebA4769 of Azoarcus sp. EbN1 of 53% (gnl|keqq|eba:ebA4769(KEGG)). Pfam: Cobalt transport protein. signal peptide. 3 TMHs; Family membership.
  
 0.952
cbiQ
Putative cobalt transport system permease protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Similar to the cobalt transport membrane protein, CbiQ in A. pleuropneumoniae; Function unclear.
  
 0.952
dppA
Part of the ABC transporter complex dppABCD involved in dipeptide import. Similar to the dipeptide periplasmic-binding protein dppA in E.coli. DIPEPTIDE-BINDING PROTEIN OF AN OSMOTIC-SHOCKABLE TRANSPORT SYSTEM. DPPA IS ALSO REQUIRED FOR PEPTIDE CHEMOTAXIS. InterPro: Bacterial extracellular solute-binding protein family 5 Signal peptide; Specificity unclear.
 
 0.946
cbiO
Putative cobalt transport system ATP-binding protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Probably responsible for the translocation of the substrate across the membrane. 40% AAA_ATPase.IPR003439; ABC_transporter. Pfam:PF00005; ABC_tran; 1. ProDom; PD000006; ABC_transporter; 1. SMART; SM00382; AAA; 1; High confidence in function and specificity.
  
 0.882
azo2910
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8FZX0 (58% identity); TREMBL:Q8U6Y9 (59% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...]
  
 
 0.848
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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