STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2065Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal peptide. 4 TMHs. (216 aa)    
Predicted Functional Partners:
norM
Multidrug resistance protein; The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae,and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. Functions as a Na(+)/drug antiporter. These proteins have 12 probable TMS,TREMBL:Q7NXN3 (35% identity); SWISSPROT:Q9K015 (32% identity). Pfam (UPF0013): Uncharacterized membrane protein family. TIGRFAM (TIGR00797): matE. TMHMM reporting 11 transmembrane helice [...]
       0.773
lexA
Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
       0.743
azo2062
Conserved hypothetical peptidyl-prolyl cis-trans isomerase. Homology to slyD of E. coli of 41% (sprot|SLYD_ECOLI) but around 30 aa at the C-terminus are missing. Peptidylprolyl isomerases accelerate protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. InterPro: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase) (IPR001179). Pfam: FKBP-type peptidyl-prolyl cis-trans isomerase. no signal peptide. no TMHs; Family membership.
       0.423
bcp1
Putative bacterioferritin comigratory protein. Homology to bcp of E. coli of 37% (srot:BCP_ECOLI) Interpro: Alkyl hydroperoxid reductase/ Thiol specific antioxidant / Mal Alergern (IPR000866) Pfam: AhpcC/TSA family no signal peptide no TMH; Family membership.
       0.423
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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