Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
prkAPutative serine protein kinase. Homology to prkA of Bacillus subtilis of 32% (gnl|keqq|bsu:BG10804). Pfam: PrkA serine kinase. This is a family of PrkA bacterial and archaeal serine kinases approximately 630 residues long. PrkA possesses the A-motif of nucleotide-binding proteins and exhibits distant homology to eukaryotic protein kinases. Note that many family members are hypothetical. Interpro: IPR010650 PrkA serine kinase. No signal peptide. No TMHs.,; Family membership. (640 aa)    
Predicted Functional Partners:
yeaH
Conserved hypothetical protein,[yeaH]54% identical (71% similarity)to SwissProt;P59349. Has PF04285(IPR006698), Protein of unknown function (DUF444);Bacterial protein of unknown function. One family member (Q97LI1) is predicted to contain a von Willebrand factor (vWF) type A domain (Smart:VWA). No Signal peptide or TMH present; Belongs to the UPF0229 family.
 
  
 0.992
ycgB
Putative cytoplasmic protein[ycgB],67% identical (79% similarity) SwissProt;P29013. TrEMBL;Q8XDL3(67% identical)TrEMBL;Q8ZP16. Has PF04293, SpoVR like protein;IPR007390; Family member P37875 is Bacillus subtilis stage V sporulation protein R,which is involved in spore cortex formation. Little is known about cortex biosynthesis, except that it depends on several sigma E controlled genes, including spoVR. No Signal peptide or TMH present; Family membership.
 
  
 0.992
azo3667
Conserved hypothetical membrane protein. Homology to RS05100 of Ralstonia solanacearum of 50% (trembl|Q8Y1D7(SRS)). Has PF05957, Bacterial protein of unknown function (DUF883);IPR010279; This family consists of several hypothetical bacterial proteins of unknown function. no signal peptide. 1 TMH; Conserved hypothetical protein.
   
    0.854
yafB
25-diketo-D-gluconic acid reductase B (EC 1.1.1.274) (25-DKG reductase B) (25-DKGR B) (25DKGR-B) (AKR5D). TREMBL:Q8Y090: 67% identity, 78% similarity. Catalyzes the reduction of 25-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG) (By similarity). subunit:monomer (by similarity). subcellular location:cytoplasmic (by similarity). 2-keto-l-gulonic acid is a key intermediate in the production of l-ascorbic acid (vitamin c). belongs to the aldo/keto reductase family InterPro:IPR001395; Aldo/ket_red. Pfam:PF00248; aldo_ket_red; 1. PRINTS PR00069; ALDKETRDTAS ribH: riboflavin sy [...]
   
    0.800
glgA
Putative glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
   
    0.723
azo2379
Hypothetical protein, 44% identity (54% similarity) to TrEMBL;Q82TM9. Has PF01636;Phosphotransferase enzyme family;IPR002575,APH_trans;This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides they include:-aminoglycoside 3'-phosphotransferase or kanamycin kinase / neomycin-kanamycin phosphotransferase and streptomycin 3''-kinase or streptomycin 3''-phosphotransferase. The aminoglycoside phosphotransferases inactivate aminoglycoside antibiotics via phosphorylation. Has PF03881,Fructosamine kinase;This family includes eukaryotic [...]
   
    0.651
azo3768
Putative catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
  
 0.614
ohr
Probable organic hydroperoxide resistance protein. Homology to ohr of X. campestris of 50% (SWISSPROT:OHR_XANAC). Organic hydroperoxide detoxification protein. Confers increased resistance to tert-butyl hydroperoxide killing. InterPro: OsmC-like protein (IPR003718) Pfam: OsmC-like protein no signal peptide no TMH; High confidence in function and specificity.
   
    0.593
azo2198
Putative PhoH-related protein,; Conserved hypothetical protein.
   
  
 0.572
wrbA1
Probable trp repressor binding protein (flavodoxin); SPROT:Q92PU3: 71% identity; 82% similarity Flavoprotein wrbA1. cofactor:binds 1 fmn per monomer (by similarity). similarity:belongs to the wrba family; contains 1 flavodoxin-like domain. InterPro:IPR008254; Flav_nitox_synth. IPR001226; Flavodoxin. Pfam: PF00258; flavodoxin; 1. Absence of signal peptide (Signal P predicted) and transmembrane helices (TMHMM predicted) met_pdase_I: methionine aminopeptidase t; High confidence in function and specificity.
   
    0.553
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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