Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo2116Probable Serine hydrolase-like protein (EC 3.1.-.-). TREMBL:Q8Y0A9: 49% identity, 63% similarity. Pfam: abhydrolase; thioesterase TIGRFAM: murB: UDP-N-acetylenolpyruvoylglucosamine No transmembrane helix (predicted by TMHMM); Function unclear. (300 aa)    
Predicted Functional Partners:
azo2114
Conserved hypothetical protein; InterPro: Sua5/YciO/YrdC/YwlC protein family TIGR00057: Sua5/YciO/YrdC/YwlC family p; High confidence in function and specificity; Belongs to the SUA5 family.
 
     0.823
trpH
Conserved hypothetical protein; TREMBL:Q7VZ25: 48% identity; 57% similarity SWISSPROT:TRPH_HAEIN:Protein trpH (38% identity). InterPro:IPR003141; PHP_N.PHP domain C-terminal region. The PHP (Polymerase and Histidinol Phosphatase) domain is a putative phosphoesterase domain. This family is often associated with an N-terminal region Pfam: PF02231; PHP_N; SMART: SM00481; POLIIIAc; thiE: thiamine-phosphate pyrophosphoryl; High confidence in function and specificity.
       0.792
lpdA
Dihydrolipoamide dehydrogenase. Homology to lpdA of N. meningitides of 70% (trembl|Q59099). THE BRANCHED-CHAIN ALPHA-KETO DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF ALPHA-KETO ACIDS TO ACYL-COA AND CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: BRANCHED-CHAIN ALPHA-KETO ACID DECARBOXYLASE (E1) LIPOAMIDE ACYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3) (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); Pyridine nucleotide-disulphide oxidoreductase, classI (IPR001100); biotin/Lipoyl attachment (IPR000089) [...]
    
 0.748
rpsO
30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
    
  0.667
ooxA
Putative opine oxidase subunit A. Homology to ooxA of A. tumefaciens of 37% (sprot|OOXA_AGRT4). OXIDATIVE CLEAVAGE OF OCTOPINE INTO L-ARGININE AND PYRUVATE (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327), NAD-bining site (IPR000205) Pfam: Pyridine nucleotide-disulphide oxidoreductase no signal peptide no TMHs; Family membership.
    
 0.652
soxF
Probable sulfide dehydrogenase, falvoprotein subunit (Flavocytochrome C flavoprotein subunit). Homology to fccB of C. vinosum of 40% (sprot|DHSU_CHRVI). Pfam: Pyridine nucleotide-disulphide oxidoreductase signal peptide no TMHs; Family membership.
    
 0.652
odhA
Probable 2-oxoglutarate dehydrogenase. Homology to odhA of A. eutrophus of 63% (sprot|ODO1_ALCEU). THE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF 2-OXOGLUTARATE TO SUCCINYL-COA & CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: 2-OXOGLUTARATE DEHYDROGENASE (E1) DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3). InterPro: Dehydrogenase E1 component (IPR001017); Transletolase (IPR005474) Tigrfam: 2oxo_dh_E1: 2-oxoglutarate dehydrogenase, E1 component Pfam: Dehydrogenase E1 component, Transketolas, pyridine binding domain [...]
    
  0.636
acpP
AcpP protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
    
 0.634
azo2113
Conserved hypothetical membrane protein. Homology to NE1726 of N.europaea of 61% (trembl:Q82TY8). InterPro: IPR008915; Peptidase_M50. Pfam: PF02163; Peptidase_M50. Non-secretory protein signal peptide probability: 0.235. TMHMM predicted 4 transmembrane helices; Conserved hypothetical protein.
       0.632
azo0065
Conserved hypothetical protein; 64% similarity with ABC-type multidrug transport system, ATPase and permease components [Dechloromonas aromatica RCB]. and.
  
     0.630
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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