STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tesA2Putative acyl-CoA thioesterase. Homology to tesA of E. coli of 32% (sprot|TESA_ECOLI) Hydrolyzes long chain acyl thioesters (c12-c18): 2-lysophosphatidylcholine + h(2)o = glycerophosphocholine + a fatty acid anion. InterPro: GDSL lipolytic enzyme (IPR001087) Pfam: Lipase/Acylhydrolase GDSL-like motif signal peptide no TMH; Family membership. (208 aa)    
Predicted Functional Partners:
azo1606
Putative inner membrane transport permease; Similar to TREMBL:Q7WGZ1 (41% identity); TREMBL:Q7W9R7 (41% identity); TREMBL:Q8XXM2 (37% identity). Pfam (DUF214): Predicted permease. TMHMM reporting 10 transmembrane helices; Specificity unclear.
 
 
   0.876
azo3026
Conserved hypothetical secreted protein. Homology to Reut02004453 of Ralstonia metallidurans of 38% (gi|48768314|ref|ZP_00272664.1|(NBCI ENTREZ)). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein.
  
 0.809
azo3245
Conserved hypothetical secreted protein. Homology to ebA4328 of Azoarcus sp. EbN1 of 59% (gnl|keqq|eba:ebA4328(KEGG)). no domains predicted. signal peptide. TMH in signal peptide.
  
 0.809
deaD
ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
     
 0.775
azo1667
Putative ABC transporter ATP-binding protein; Similar to TREMBL:Q82UM8 (55% identity); TREMBL:Q8XYP0 (59% identity); TREMBL:Q7W685 (59% identity). Pfam (PF00005): ABC transporter; Specificity unclear.
 
 
   0.716
eglA
Putative endoglucanase precursor; 41% Glyco_hydro_5. Pfam:PF00150; Cellulase; 1. Signal peptide: present; High confidence in function and specificity; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
   
 0.696
spr1
Putative glucan 1,3-beta-glucosidase; Glucan 13-beta-glucosidase precursor (EC 3.2.1.58) (Exo-13-beta- glucanase).BETA-GLUCANASES PARTICIPATE IN THE METABOLISM OF BETA-GLUCAN THE MAIN STRUCTURAL COMPONENT OF THE CELL WALL. IT COULD ALSO FUNCTION BIOSYNTHETICALLY AS A TRANSGLYCOSYLASE. 33% Glyco_hydro_5. Pfam:PF00150; Cellulase; 1; High confidence in function and specificity; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
   
 0.696
srkA
Conserved hypothetical protein; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
 
     0.632
azo0699
Hypothetical secreted protein. No significant homology to the data bank. no domains pedicted. signal peptide. TMH in signal peptide.
    
  0.502
azo1264
Putative transmembrane sensor protein, no similarity to other bacterial proteins. Best hits to mus musculus and homo sapiens. Domains (LCCL_dom and TIR) are found in proteins (animal and plants) involved in protection against bacterial infection. InterPro: IPR004043 LCCL_dom. IPR000157 TIR. TMHMM reporting 1 transmembrane helices.
    
  0.502
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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