STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2128GGDEF-domain containing protein,; Conserved hypothetical protein. (471 aa)    
Predicted Functional Partners:
azo1490
Conserved hypothetical signaling protein. Homology to ebA6472 Azoarcus sp. EbN1 of 36% (gnl|keqq|eba:ebA6472(KEGG)). InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. IPR001789 Response_reg. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF01590 GAF domain. PF00563 EAL domain. PF00072 Response_reg. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain. No signal peptide. No TMHs; Conserved hypothetical protein.
 
0.849
azo3381
Hypothetical signaling protein.
 
0.839
barA
Putative sensor-regulator protein,; Specificity unclear.
 0.832
gacS
Putative two-component hybrid sensor and regulator,; Family membership.
 0.829
azo2482
Putative hybrid sensor and regulator; Gene function unknown, no significant homology to proteins of known function. Typical domains for hybrid sensor and regulator are found. InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR001789 Response_reg. IPR008207 Hpt. IPR000014 PAS_domain. IPR001610 PAC. Pfam: PF00072 Response_reg. PF02518 HATPase_c. PF00512 HisKA. PF00989 PAS. PF00785 PAC. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00448 REC. SM00091 PAS SM00086 PAC. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal pepti [...]
 
 0.826
azo3685
Putative hybrid sensor and regulator protein, MmoS) InterPro: IPR003594; ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR008207; Hpt. IPR001610; PAC. IPR000700; PAS-assoc_C. IPR000014; PAS_domain. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00785; PAC. PF00989; PAS. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00073; HPT. SM00086; PAC. SM00091; PAS. SM00448; REC. TIGRFAM: TIGR00229; sensory_box. TMHMM reporting 2 transmembrane helices; Family membership.
 0.822
azo1486
Conserved hypothetical signaling protein. Homology to TdenA01000705 of Thiobacillus denitrificans of 61% (gi|52008401|ref|ZP_00335778.1|(NBCI ENTREZ)). Pfam: PF01590 GAF domain. PF00563 EAL domain. No signal peptide. No TMHs; Conserved hypothetical protein.
 
 
 0.812
azo2457
Putative sensory box histidine kinase,; Function unclear.
 
 0.812
azo3665
Conserved hypothetical signaling protein. Homology to IL2267 of Idiomarina loihiensis of 35% (gnl|keqq|ilo:IL2267(KEGG)). InterPro: IPR001633 EAL. IPR000160 GGDEF. Pfam: PF00563 EAL. PF00990 GGDEF. SMART: SM00267 DUF1. SM00052 DUF2. TIGRFAM:TIGR00254 GGDEF. Signaling protein ykoW. Probable signaling protein whose physiological role is not yet known. no signal peptide. No TMHs; Conserved hypothetical protein.
  
 
  0.803
azo0335
EAL-domain containing protein, ):This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function [1]. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site; Conserved hypothetical protein.
 
 
 0.783
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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