| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo0335 | azo1490 | azo0335 | azo1490 | EAL-domain containing protein, ):This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function [1]. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site; Conserved hypothetical protein. | Conserved hypothetical signaling protein. Homology to ebA6472 Azoarcus sp. EbN1 of 36% (gnl|keqq|eba:ebA6472(KEGG)). InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. IPR001789 Response_reg. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF01590 GAF domain. PF00563 EAL domain. PF00072 Response_reg. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain. No signal peptide. No TMHs; Conserved hypothetical protein. | 0.830 |
| azo0335 | azo2128 | azo0335 | azo2128 | EAL-domain containing protein, ):This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function [1]. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site; Conserved hypothetical protein. | GGDEF-domain containing protein,; Conserved hypothetical protein. | 0.783 |
| azo0335 | azo2457 | azo0335 | azo2457 | EAL-domain containing protein, ):This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function [1]. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site; Conserved hypothetical protein. | Putative sensory box histidine kinase,; Function unclear. | 0.649 |
| azo0335 | azo2482 | azo0335 | azo2482 | EAL-domain containing protein, ):This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function [1]. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site; Conserved hypothetical protein. | Putative hybrid sensor and regulator; Gene function unknown, no significant homology to proteins of known function. Typical domains for hybrid sensor and regulator are found. InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR001789 Response_reg. IPR008207 Hpt. IPR000014 PAS_domain. IPR001610 PAC. Pfam: PF00072 Response_reg. PF02518 HATPase_c. PF00512 HisKA. PF00989 PAS. PF00785 PAC. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00448 REC. SM00091 PAS SM00086 PAC. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal pepti [...] | 0.829 |
| azo0335 | azo3381 | azo0335 | azo3381 | EAL-domain containing protein, ):This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function [1]. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site; Conserved hypothetical protein. | Hypothetical signaling protein. | 0.843 |
| azo0335 | azo3665 | azo0335 | azo3665 | EAL-domain containing protein, ):This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function [1]. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site; Conserved hypothetical protein. | Conserved hypothetical signaling protein. Homology to IL2267 of Idiomarina loihiensis of 35% (gnl|keqq|ilo:IL2267(KEGG)). InterPro: IPR001633 EAL. IPR000160 GGDEF. Pfam: PF00563 EAL. PF00990 GGDEF. SMART: SM00267 DUF1. SM00052 DUF2. TIGRFAM:TIGR00254 GGDEF. Signaling protein ykoW. Probable signaling protein whose physiological role is not yet known. no signal peptide. No TMHs; Conserved hypothetical protein. | 0.432 |
| azo0335 | azo3685 | azo0335 | azo3685 | EAL-domain containing protein, ):This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function [1]. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site; Conserved hypothetical protein. | Putative hybrid sensor and regulator protein, MmoS) InterPro: IPR003594; ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR008207; Hpt. IPR001610; PAC. IPR000700; PAS-assoc_C. IPR000014; PAS_domain. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00785; PAC. PF00989; PAS. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00073; HPT. SM00086; PAC. SM00091; PAS. SM00448; REC. TIGRFAM: TIGR00229; sensory_box. TMHMM reporting 2 transmembrane helices; Family membership. | 0.760 |
| azo0335 | barA | azo0335 | azo2402 | EAL-domain containing protein, ):This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function [1]. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site; Conserved hypothetical protein. | Putative sensor-regulator protein,; Specificity unclear. | 0.829 |
| azo0335 | gacS | azo0335 | azo2575 | EAL-domain containing protein, ):This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function [1]. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site; Conserved hypothetical protein. | Putative two-component hybrid sensor and regulator,; Family membership. | 0.829 |
| azo1486 | azo1490 | azo1486 | azo1490 | Conserved hypothetical signaling protein. Homology to TdenA01000705 of Thiobacillus denitrificans of 61% (gi|52008401|ref|ZP_00335778.1|(NBCI ENTREZ)). Pfam: PF01590 GAF domain. PF00563 EAL domain. No signal peptide. No TMHs; Conserved hypothetical protein. | Conserved hypothetical signaling protein. Homology to ebA6472 Azoarcus sp. EbN1 of 36% (gnl|keqq|eba:ebA6472(KEGG)). InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. IPR001789 Response_reg. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF01590 GAF domain. PF00563 EAL domain. PF00072 Response_reg. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain. No signal peptide. No TMHs; Conserved hypothetical protein. | 0.833 |
| azo1486 | azo2128 | azo1486 | azo2128 | Conserved hypothetical signaling protein. Homology to TdenA01000705 of Thiobacillus denitrificans of 61% (gi|52008401|ref|ZP_00335778.1|(NBCI ENTREZ)). Pfam: PF01590 GAF domain. PF00563 EAL domain. No signal peptide. No TMHs; Conserved hypothetical protein. | GGDEF-domain containing protein,; Conserved hypothetical protein. | 0.812 |
| azo1486 | azo2457 | azo1486 | azo2457 | Conserved hypothetical signaling protein. Homology to TdenA01000705 of Thiobacillus denitrificans of 61% (gi|52008401|ref|ZP_00335778.1|(NBCI ENTREZ)). Pfam: PF01590 GAF domain. PF00563 EAL domain. No signal peptide. No TMHs; Conserved hypothetical protein. | Putative sensory box histidine kinase,; Function unclear. | 0.649 |
| azo1486 | azo2482 | azo1486 | azo2482 | Conserved hypothetical signaling protein. Homology to TdenA01000705 of Thiobacillus denitrificans of 61% (gi|52008401|ref|ZP_00335778.1|(NBCI ENTREZ)). Pfam: PF01590 GAF domain. PF00563 EAL domain. No signal peptide. No TMHs; Conserved hypothetical protein. | Putative hybrid sensor and regulator; Gene function unknown, no significant homology to proteins of known function. Typical domains for hybrid sensor and regulator are found. InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR001789 Response_reg. IPR008207 Hpt. IPR000014 PAS_domain. IPR001610 PAC. Pfam: PF00072 Response_reg. PF02518 HATPase_c. PF00512 HisKA. PF00989 PAS. PF00785 PAC. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00448 REC. SM00091 PAS SM00086 PAC. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal pepti [...] | 0.829 |
| azo1486 | azo3381 | azo1486 | azo3381 | Conserved hypothetical signaling protein. Homology to TdenA01000705 of Thiobacillus denitrificans of 61% (gi|52008401|ref|ZP_00335778.1|(NBCI ENTREZ)). Pfam: PF01590 GAF domain. PF00563 EAL domain. No signal peptide. No TMHs; Conserved hypothetical protein. | Hypothetical signaling protein. | 0.840 |
| azo1486 | azo3665 | azo1486 | azo3665 | Conserved hypothetical signaling protein. Homology to TdenA01000705 of Thiobacillus denitrificans of 61% (gi|52008401|ref|ZP_00335778.1|(NBCI ENTREZ)). Pfam: PF01590 GAF domain. PF00563 EAL domain. No signal peptide. No TMHs; Conserved hypothetical protein. | Conserved hypothetical signaling protein. Homology to IL2267 of Idiomarina loihiensis of 35% (gnl|keqq|ilo:IL2267(KEGG)). InterPro: IPR001633 EAL. IPR000160 GGDEF. Pfam: PF00563 EAL. PF00990 GGDEF. SMART: SM00267 DUF1. SM00052 DUF2. TIGRFAM:TIGR00254 GGDEF. Signaling protein ykoW. Probable signaling protein whose physiological role is not yet known. no signal peptide. No TMHs; Conserved hypothetical protein. | 0.443 |
| azo1486 | azo3685 | azo1486 | azo3685 | Conserved hypothetical signaling protein. Homology to TdenA01000705 of Thiobacillus denitrificans of 61% (gi|52008401|ref|ZP_00335778.1|(NBCI ENTREZ)). Pfam: PF01590 GAF domain. PF00563 EAL domain. No signal peptide. No TMHs; Conserved hypothetical protein. | Putative hybrid sensor and regulator protein, MmoS) InterPro: IPR003594; ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR008207; Hpt. IPR001610; PAC. IPR000700; PAS-assoc_C. IPR000014; PAS_domain. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00785; PAC. PF00989; PAS. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00073; HPT. SM00086; PAC. SM00091; PAS. SM00448; REC. TIGRFAM: TIGR00229; sensory_box. TMHMM reporting 2 transmembrane helices; Family membership. | 0.760 |
| azo1486 | barA | azo1486 | azo2402 | Conserved hypothetical signaling protein. Homology to TdenA01000705 of Thiobacillus denitrificans of 61% (gi|52008401|ref|ZP_00335778.1|(NBCI ENTREZ)). Pfam: PF01590 GAF domain. PF00563 EAL domain. No signal peptide. No TMHs; Conserved hypothetical protein. | Putative sensor-regulator protein,; Specificity unclear. | 0.829 |
| azo1486 | gacS | azo1486 | azo2575 | Conserved hypothetical signaling protein. Homology to TdenA01000705 of Thiobacillus denitrificans of 61% (gi|52008401|ref|ZP_00335778.1|(NBCI ENTREZ)). Pfam: PF01590 GAF domain. PF00563 EAL domain. No signal peptide. No TMHs; Conserved hypothetical protein. | Putative two-component hybrid sensor and regulator,; Family membership. | 0.829 |
| azo1490 | azo0335 | azo1490 | azo0335 | Conserved hypothetical signaling protein. Homology to ebA6472 Azoarcus sp. EbN1 of 36% (gnl|keqq|eba:ebA6472(KEGG)). InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. IPR001789 Response_reg. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF01590 GAF domain. PF00563 EAL domain. PF00072 Response_reg. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain. No signal peptide. No TMHs; Conserved hypothetical protein. | EAL-domain containing protein, ):This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function [1]. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site; Conserved hypothetical protein. | 0.830 |
| azo1490 | azo1486 | azo1490 | azo1486 | Conserved hypothetical signaling protein. Homology to ebA6472 Azoarcus sp. EbN1 of 36% (gnl|keqq|eba:ebA6472(KEGG)). InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. IPR001789 Response_reg. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF01590 GAF domain. PF00563 EAL domain. PF00072 Response_reg. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain. No signal peptide. No TMHs; Conserved hypothetical protein. | Conserved hypothetical signaling protein. Homology to TdenA01000705 of Thiobacillus denitrificans of 61% (gi|52008401|ref|ZP_00335778.1|(NBCI ENTREZ)). Pfam: PF01590 GAF domain. PF00563 EAL domain. No signal peptide. No TMHs; Conserved hypothetical protein. | 0.833 |