STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2136Hypothetical protein ypjD. TREMBL:Q7W7V7: 56% identity, 65% similarity SPROT:YPJD_BACSU:P42979: 27% identity, 49% similarity This group of prokaryotic proteins has no known function. It includes the uncharacterized protein MazG in Escherichia coli. InterPro:IPR004518; MazG. Pfam: PF03819 No transmembrane helices (TMHMM predicted); Specificity unclear. (117 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
  0.713
rlmJ
Conserved hypothetical protein; Specifically methylates the adenine in position 2030 of 23S rRNA.
       0.630
azo2135
Putative phosphate permease; Probable low-affinity phosphate transporter protein.Involved in phosphate transport depending on the proton motive force. InterPro: Phosphate transporter family Similar to PitA a cation-phosphate transporter in E.coli. No signal peptide; High confidence in function and specificity.
       0.601
azo2134
Hypothetical protein, has no good homology over the entire length with hits in Database. TrEMBL Q9HT58 Hypothetical protein PA5515 [PA5515] [Pseudomonas aeruginosa. No Signal Peptide or TMH being reported as present; Family membership.
       0.596
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily.
    
  0.564
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.493
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.475
azo1483
Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its [...]
    
  0.474
dcd
dCTP deaminase; Catalyzes the deamination of dCTP to dUTP.
    
  0.474
hpt
Hypoxanthine phosphoribosyltransferase (Hypoxanthine-guanine phosphoribosyltransferase. (HGPRTase) (IMP pyrophosphorylase) (IMP diphosphorylase) (Transphosphoribosidase) (Guanine phosphoribosyltransferase); Function unclear.
    
  0.474
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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