STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
azo2138Hypothetical protein PA3753. A variety of bacterial transferases contain a repeat structure composed of tandem repeats of a [LIV]-G-X(4) hexapeptide, which, in the tertiary structure of LpxA (UDP N-acetylglucosamine acyltransferase) [1], has been shown to form a left-handed parallel beta helix TREMBL:Q9A526: 55% identity; 75% similarity bacterial transferase family protein. Superfamily: ferripyochelin binding protein InterPro:IPR001451; Hexapep_transf.Bacterial transferase hexapeptide repeat Pfam:PF00132; Hexapep; presence of DUF99 domain. No signal peptide (Signal P) or transmembrane [...] (181 aa)    
Predicted Functional Partners:
azo3977
Putative carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
    
 0.914
ppa
Probable inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
      0.565
azo2139
Conserved hypothetical secreted protein. Homology to CV3305 of C.violaceum of 37% (tremble:Q7NSW4). Has PF04402, Protein of unknown function (DUF541);IPR007497:Members of this family have so far been found in bacteria and mouse SwissProt or TrEMBL entries. However possible family members have also been identified in translated rat (Genbank:AW144450) and human (Genbank:AI478629) ESTs. A mouse family member has been named SIMPL (signalling molecule that associates with mouse pelle-like kinase). SIMPL appears to facilitate and/or regulate complex formation between IRAK/mPLK (IL-1 receptor [...]
       0.525
rlmJ
Conserved hypothetical protein; Specifically methylates the adenine in position 2030 of 23S rRNA.
       0.494
mnaA
UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) (UDP-GlcNAc-2- epimerase). Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc) the activated donor of ManNAc residues (By similarity). InterPro: UDP-N-acetylglucosamine 2-epimerase; High confidence in function and specificity.
    
  0.456
azo2140
Conserved hypothetical secreted protein. Homology to ebD110 of Azoarcus sp. EbN1 of 46% (gnl|keqq|eba:ebD110(KEGG)). No domains predicted. No TMHs. Signal peptide present; Conserved hypothetical protein.
       0.430
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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