STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2140Conserved hypothetical secreted protein. Homology to ebD110 of Azoarcus sp. EbN1 of 46% (gnl|keqq|eba:ebD110(KEGG)). No domains predicted. No TMHs. Signal peptide present; Conserved hypothetical protein. (101 aa)    
Predicted Functional Partners:
azo2139
Conserved hypothetical secreted protein. Homology to CV3305 of C.violaceum of 37% (tremble:Q7NSW4). Has PF04402, Protein of unknown function (DUF541);IPR007497:Members of this family have so far been found in bacteria and mouse SwissProt or TrEMBL entries. However possible family members have also been identified in translated rat (Genbank:AW144450) and human (Genbank:AI478629) ESTs. A mouse family member has been named SIMPL (signalling molecule that associates with mouse pelle-like kinase). SIMPL appears to facilitate and/or regulate complex formation between IRAK/mPLK (IL-1 receptor [...]
       0.651
azo2141
Conserved hypothetical secreted protein. Homology to CV2523 of Chromobacterium violaceum of 48% (trembl:Q7NV23). Pfam: NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins. Signal peptide. No TMHs; Conserved hypothetical protein.
       0.598
azo2138
Hypothetical protein PA3753. A variety of bacterial transferases contain a repeat structure composed of tandem repeats of a [LIV]-G-X(4) hexapeptide, which, in the tertiary structure of LpxA (UDP N-acetylglucosamine acyltransferase) [1], has been shown to form a left-handed parallel beta helix TREMBL:Q9A526: 55% identity; 75% similarity bacterial transferase family protein. Superfamily: ferripyochelin binding protein InterPro:IPR001451; Hexapep_transf.Bacterial transferase hexapeptide repeat Pfam:PF00132; Hexapep; presence of DUF99 domain. No signal peptide (Signal P) or transmembrane [...]
       0.430
azo2142
Hypothetical protein MK0525 (OrfX). trembl|Q9V230 (Q9V230) Inosine-5'-monophosphate dehydrogenase related; 34% identity, 55% similarity. InterPro: CBS domain (IPR005857, IPR004840) TIGRFAM: kpsF/GutQ family TMHMM predicted absence of transmembrane helices; Specificity unclear.
       0.410
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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