STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
enoPutative enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)    
Predicted Functional Partners:
pykA
Pyruvate kinase (PK) catalyses the final step in glycolysis, the conversion of phosphoenolpyruvate to pyruvate with concomitant phosphorylation of ADP to ATP:ADP + phosphoenolpyruvate = ATP + pyruvate. 52% Pyruvate_kinase. Pfam:PF00224; PK; 1.PF02887; PK_C; 1. TIGRFAMs:TIGR01064; pyruv_kin; 1; High confidence in function and specificity.
 
 0.995
pgk
Phosphoglycerate kinaseis an enzyme that catalyses the formation of ATP to ADP and viceversa. In the second step of the second phase in glycolysis, 1,3-diphosphoglycerate is converted to 3-phosphoglycerate,forming one molecule of ATP. If the reverse were to occur,one molecule of ADP would be formed. 59% PGK. Pfam:PF00162; PGK; 1; High confidence in function and specificity.
 
 
 0.994
pgi
Glucose-6-phosphate isomerase 1(EC 5.3.1.9) (GPI 1)(Phosphoglucose isomerase 1)(PGI 1)(Phosphohexose isomerase 1) (PHI 1). Enzyme involved in glycolysis and in gluconeogenesis.Catalytic activity: d-glucose 6-phosphate = d-fructose 6- phosphate.Belongs to the gpi family. 39% G6P_Isomerase. Pfam:PF00342; PGI; 1; High confidence in function and specificity.
  
 0.990
gpmA
Putative phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
  
 0.989
fba
Putative fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 0.989
tim
Putative triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 
 0.988
gapA
Glyceraldehyde-3-phosphate dehydrogenase(GAPDH)plays an important role in glycolysis and gluconeogenesis by reversibly catalysing the oxidation and phosphorylation of D-glyceraldehyde-3-phosphate to 1,3-diphospho-glycerate.61% GAPDH-I.IPR000173; GAP_dhdrogenase. Pfam:PF02800; Gp_dh_C; 1.PF00044; Gp_dh_N; 1. TIGRFAMs:TIGR01534; GAPDH-I; 1; High confidence in function and specificity.
 
 0.984
gapB
D-erythrose 4-phosphate dehydrogenase(E4PDH), GapB protein. Could play a role in pyridoxal 5-phosphate synthesis.Involved in the reaction: d-erythrose 4-phosphate + nad(+) = 4-phosphoerythronate + nadh. 51% E4PD_g-proteo.IPR000173; GAP_dhdrogenase. Pfam:PF00044; gpdh; 1.PF02800; gpdh_C; 1. TIGR00274: glucokinase regulator-relate. TIGRFAMs:TIGR01532; E4PD_g-proteo; 1; High confidence in function and specificity.
 
 0.981
tkt
Putative transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.979
rplD
50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
 
 0.974
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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