STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msrBConserved hypothetical peptide methionine sulfoxide reductase. Homology to msrB of S. elongatus of 64%. Peptide methionine sulphoxide reductase reverses the inactivation of many proteins due to the oxidation of critical methionine residues by reducing methionine sulphoxide, Met(O), to methionine. InterPro: Domain of unknown function DUF25 (IPR002579). Pfam: Domain of unknown function DUF25. Tigrfam: TIGR00357: PilB-related protein. no TMHs; Family membership. (138 aa)    
Predicted Functional Partners:
msrA
Putative peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.995
cutA2
Putative protein disulfide-isomerase; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
   
 
 0.896
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
 
 0.829
cyaY
Putative CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
    
   0.811
rplK
50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
 
 0.792
rpmG
50S ribosomal protein L33; Family membership; Belongs to the bacterial ribosomal protein bL33 family.
    
 
 0.790
azo0052
Hypothetical secreted protein. No homology of the entire protein to the data bank. InterPro:Esterase/lipase/thioesterase family active site Pfam:Putative serine esterase (DUF676) This family of proteins are probably serine esterase type enzymes. Signal peptide present (Signal P predicted) No transmembrane helices.
    
   0.789
rpmB
50S ribosomal protein L28; High confidence in function and specificity; Belongs to the bacterial ribosomal protein bL28 family.
    
   0.789
rpsI
30S ribosomal protein S9; High confidence in function and specificity; Belongs to the universal ribosomal protein uS9 family.
   
   0.789
rpsP
30S ribosomal protein S16; High confidence in function and specificity; Belongs to the bacterial ribosomal protein bS16 family.
    
   0.789
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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