STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilY1APutative type 4 pilus biogenesis protein; PilY1 is a large protein with C-terminal homology to the PilC2 protein of Neisseria gonorrhoeae, thought to be a fimbrial tip-associated adhesin, and which, like PilY1, is involved in fimbrial assembly. Similar to trembl|Q8XW00 (31%). Pfam (PF01839): FG-GAP repeat SignalP reporting Signal peptide; Function unclear. (1124 aa)    
Predicted Functional Partners:
pilW
Putative type 4 pilus biogenesis protein; In Pseudomonas aeruginosa, the PilW and PilX proteins are membrane located, possess the hydrophobic N-terminus characteristic of prepilin-like proteins, and appear to belong to the GspJ and GspK group of proteins that are required for protein secretion in a wide range of Gram-negative bacteria. These findings increase the similarities between the fimbrial biogenesis and the Gsp-based protein-secretion supersystems. Similar to trembl|Q8XVZ8 (29%). Smart (SM00438): Repressor of transcription TMHMM reporting one TMH. SignalP reporting Signal pepti [...]
 
  
 0.979
azo2178
probABLE TYPE 4 FIMBRIAL BIOGENESIS RELATEDTRANSMEMBRANE PROTEIN; Family membership.
 
  
 0.975
azo2179
Conserved hypothetical protein; Probable type-4 fimbrial pilin related signal peptide protein,32% Identity to TrEMBL;Q8XVZ6,Q7NTE6. Has Signal peptide. Has COG4970, FimT, Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion].
 
  
 0.933
azo2180
Conserved hypothetical prepilin like protein; In P. aeruginosa PilE is probable involved in pilus biogenesis and in twitching motility. Similarity to PilE of Ralstonia eutropha (33%) TMHMM reporting one TMhelix. Pfam: pilin domain; Conserved hypothetical protein.
 
  
 0.874
fimT
Putative pre-pilin like protein; In P. aeruginosa fimT and fimU genes contain prepilin-like leader sequences. FimT plays probable a role in fimbrial biogenesis. Similar to trembl|Q87FA9 (30%). Pfam (PF00114): Pilin (bacterial filament) TMHMM reporting one TMH. SignalP reporting Signal peptide; Function unclear.
 
  
 0.796
azo2176
Hypothetical secreted protein. Homology to RS00045 of R. solanacearum of 25% (trembl|Q8XVZ9(SRS)) No domains predicted Sinal P reporting singal peptide present. No TMH being reported.
       0.778
azo2461
Conserved hypothetical protein. Homology to mll6889 of M.loti. of 58% (trembl|Q987V8(SRS)). No domains predicted. No TMHs. No signal peptide.
  
     0.732
pilX
Putative Tfp pilus assembly protein; In P. aeruginosa the PilW and PilX proteins are membrane located, possess the hydrophobic N-terminus characteristic of prepilin-like proteins, and appear to belong to the GspJ and GspK group of proteins that are required for protein secretion in a wide range of Gram-negative bacteria. These genes are involved in the assembly of type 4 fimbriae. Similar to trembl|Q8PJ76 (34%). TMHMM reporting one TMH. SignalP reporting Signal peptide; Function unclear.
  
  
 0.728
azo2591
Conserved hypothetical secreted protein. Homology to Daro03002418 of Dechloromonas aromatica of 58% (gi|53730135|ref|ZP_00150721.2|(NBCI ENTREZ)). No domains predicted. No TMHs. signal peptide present.
  
     0.695
azo3166
Hypothetical Protein,20% identity to TrEMBL;Q9HUK7. Very Bad homology with the hits in the DB over entire length of protein. No substantial good hits available. No signal peptide or TMH reported present.
  
     0.690
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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