STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2179Conserved hypothetical protein; Probable type-4 fimbrial pilin related signal peptide protein,32% Identity to TrEMBL;Q8XVZ6,Q7NTE6. Has Signal peptide. Has COG4970, FimT, Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion]. (135 aa)    
Predicted Functional Partners:
azo2178
probABLE TYPE 4 FIMBRIAL BIOGENESIS RELATEDTRANSMEMBRANE PROTEIN; Family membership.
 
  
 0.944
pilW
Putative type 4 pilus biogenesis protein; In Pseudomonas aeruginosa, the PilW and PilX proteins are membrane located, possess the hydrophobic N-terminus characteristic of prepilin-like proteins, and appear to belong to the GspJ and GspK group of proteins that are required for protein secretion in a wide range of Gram-negative bacteria. These findings increase the similarities between the fimbrial biogenesis and the Gsp-based protein-secretion supersystems. Similar to trembl|Q8XVZ8 (29%). Smart (SM00438): Repressor of transcription TMHMM reporting one TMH. SignalP reporting Signal pepti [...]
 
  
 0.939
pilY1A
Putative type 4 pilus biogenesis protein; PilY1 is a large protein with C-terminal homology to the PilC2 protein of Neisseria gonorrhoeae, thought to be a fimbrial tip-associated adhesin, and which, like PilY1, is involved in fimbrial assembly. Similar to trembl|Q8XW00 (31%). Pfam (PF01839): FG-GAP repeat SignalP reporting Signal peptide; Function unclear.
 
  
 0.933
azo2180
Conserved hypothetical prepilin like protein; In P. aeruginosa PilE is probable involved in pilus biogenesis and in twitching motility. Similarity to PilE of Ralstonia eutropha (33%) TMHMM reporting one TMhelix. Pfam: pilin domain; Conserved hypothetical protein.
 
  
 0.841
azo2176
Hypothetical secreted protein. Homology to RS00045 of R. solanacearum of 25% (trembl|Q8XVZ9(SRS)) No domains predicted Sinal P reporting singal peptide present. No TMH being reported.
    
 0.735
pilV
Putative prepilin-like protein; In P. aeruginosa the genes pilV and pilE encode prepilin-like proteins involved in type 4 fimbrial biogenesis. Similar to trembl|Q8PJ74 (46%). SignalP reporting Signal Peptide; Function unclear.
 
  
 0.572
azo1093
Conserved hypothetical membrane protein. Homology to RS03012 of Ralstonia solanacearum of 40% (trembl|Q8XTJ8) InterPro: Protein of unknown function DUF58 This domain is found in a family of prokaryotic proteins that have no known function. Proteins belonging to this family include hypothetical proteins from eubacteria and archaebacteria. Some of these proteins also contain the Von Willebrand factor, type A domain InterterPro: IPR002881; DUF58. Pfam: PF01882; DUF58; Non-secretory with low signal peptide probability (Signal P predicted). TMHMM predicted 2 transmembrane helices; Conserved [...]
  
     0.562
pilY1B
Putative Tfp pilus assembly protein; PilY1 is a large protein with C-terminal homology to the PilC2 protein of Neisseria gonorrhoeae, thought to be a fimbrial tip-associated adhesin, and which, like PilY1, is involved in fimbrial assembly. PilY1 appears to be located in both the membrane and the external fimbrial fractions. Similar to pir|H82802 (39%). SignalP reporting Signal peptide; Function unclear.
 
  
 0.560
fimT
Putative pre-pilin like protein; In P. aeruginosa fimT and fimU genes contain prepilin-like leader sequences. FimT plays probable a role in fimbrial biogenesis. Similar to trembl|Q87FA9 (30%). Pfam (PF00114): Pilin (bacterial filament) TMHMM reporting one TMH. SignalP reporting Signal peptide; Function unclear.
 
     0.558
pilE
Putative prepilin like protein; In P. aeruginosa PilE is probable involved in pilus biogenesis and in twitching motility. Similar to trembl|Q82TX3 (50%) and to pir|G82857 (43%). Pfam (PF00114): Pilin (bacterial filament) SignalP reporting Signal peptide. TMHMM reporting one Tmhelix; Function unclear.
 
  
 0.538
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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