STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
yaiEConserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (107 aa)    
Predicted Functional Partners:
pyrR
Phosphoribosyl transferase or bifunctional regulator/uracil phosphoribosyltransferase; High confidence in function and specificity.
     
 0.874
azo1019
Conserved hypothetical protein. Homology to CV2191 of C.violaceum of 64% (tremble:Q7NVZ9). Has PF02578,Uncharacterised ACR, YfiH family COG1496. InterPro;IPR003730. No signal peptide. No TMHs. TIGR00726: conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.
     
  0.855
surE
Phosphoric-monoester phosphohydrolase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.855
guaD
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
     
 0.855
hpt
Hypoxanthine phosphoribosyltransferase (Hypoxanthine-guanine phosphoribosyltransferase. (HGPRTase) (IMP pyrophosphorylase) (IMP diphosphorylase) (Transphosphoribosidase) (Guanine phosphoribosyltransferase); Function unclear.
     
  0.855
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
     
  0.854
azo2185
Conserved hypothetical membrane protein. Homology to NMA1807 of Neisseria meningitidis of 41% (trembl|Q9JTE8(SRS)). No domains predicted. TMHMM reporting 2 TMH present. NO Signal Peptide being reported present; Conserved hypothetical protein.
       0.802
azo2048
Hypothetical protein yfdR. The HD domain is found in a superfamily of enzymes with a predicted or known phosphohydrolase activity. These enzymes appear to be involved in the nucleic acid metabolism, signal transduction and possibly other functions in bacteria,archaea and eukaryotes TREMBL:Q8HAA3: 41% identity,52% similarity InterPro:IPR003607; Met_phsphohydro. SMART:SM00471; HDc hstdl_phs_rel: histidinol phosphatase-r No signal peptide No transmembrane helices; Function unclear.
     
  0.792
azo2183
Conserved hypothetical protein, 57% identity(77% Similarity) to SwissProt;Q8XWC5. SwissProt;Q82SQ9(60% identity) Has (IPR007551)PF04461, Protein of unknown function (DUF520);Family of uncharacterised proteins. Signal Peptide or TMH not present; Specificity unclear; Belongs to the UPF0234 family.
       0.791
argG
ArgG protein; Argininosuccinate synthase, argG. Similar to SWISSPROT:ASSY_NITEU (81%). Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate. InterPro (PF00764): Argininosuccinate synthase InterPro (TIGR00032): Argininosuccinate synthase; High confidence in function and specificity.
       0.779
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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