Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
azo2195Probable flavoprotein; Hypothetical protein yhiN. FAD flavoproteins belong to the family of pyridine nucleotide-disulphide oxidoreductases TREMBL:Q7MBF1: 58% identity, 69% similarity InterPro: IPR001327; FAD_pyr_redox. IPR004792; HI0933_like. IPR000205; NAD_BS. IPR001100; Pyr_redox InterPro: HI0933-like protein Pfam:PF03486; HI0933_like; 1. TIGR00275: conserved hypothetical pro Non-secretory protein with signal peptide probability of 0.464 Absence of transmembrane helices (TMHMM predicted); Specificity unclear. (402 aa)    
Predicted Functional Partners:
azo2196
Metallo-phosphoesterase, 50% identity(67% similarity) to TrEMBL;Q6N2S9. TrEMBL;Q885N2(53% identity). Has PF00149, Calcineurin-like phosphoesterase;IPR004843,M-pesterase:This family includes a diverse range of phosphoesterases, including protein phosphoserine phosphatases, nucleotidases, sphingomyelin phosphodiesterases and 2'-3' cAMP phosphodiesterases as well as nucleases such as bacterial SbcD P13457 or yeast MRE11 P32829. The most conserved regions in this superfamily centre around the metal chelating residues. The metallo-phosphoesterase motif is found in a large number of proteins [...]
       0.561
azo2194
Conserved hypothetical membrane protein. Homology to rs04519 of R. solanacearum of 33% (trembl|Q8Y0Z7(SRS)). no domains predicted. no signal peptide. 1 TMHs; Conserved hypothetical protein.
       0.527
paaE
Probable phenylacetic acid degradation NADH oxidoreductase paaE. Homology to paaE of E. coli of 50% (sprot|PAAE_ECOLI). Probable PART OF A MULTICOMPONENT OXYGENASE involved in aerobic degradation of phenylacetic acid. InterPro: Oxidoreductase FAD and NAD(P)-binding domain(IPR001433); 2Fe-2S Ferredoxin (IPR006057); Ferredoxin (IPR001041); NADH: cytochrome b5 reductase (CBR) (IPR001834) Pfam: Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain; 2Fe-2S iorn-sulfur cluster binding domain no signal peptide no TMHs; High confidence in function and specificity.
     
  0.449
vanB1
Probable vanillate O-demethylase oxidoreductase (Vanillate degradation ferredoxin-like protein). Homology to vanB of P. sp HR199 of 40% (sprot|VANB_PSEUH). The vanillate demethylase (EC:1.14.13.82) consists of two proteins: an oxygenase and an oxygenase reductase (VanA and VanB). This enzyme is involved in the vanillate degradation, a key intermediate in the degradation of lignin. InterPro: NADH:cytochrome b5 reductase (CBR)(IPR001834); Ferredoxin (IPR001041); Oxidoreductase FAD and NAD(P) binding domain (IPR001433) Pfam: Oxidoredutase FAD-binding domain; Oxidoreductase NAD-binding dom [...]
     
  0.449
azo1828
Hypothetical secreted protein. No significant homology over the entire protein length with the data bank. InterPro: Oxidoreductase FAD and NAD(P)-binding domain (IPR001433); Ferredoxin (IPR001041); NADH: cytochrome b5 reductase (IPR001834). Pfam: Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain; 2Fe-2S iron-sulfur cluster binding domain. signal peptide. no TMHs.
     
  0.449
oxoR
Reductase component OxoR, of the 2-oxo-1,2-dihydroquinoline 8 monooxygenase protein. Enzyme involved in the second step of quinoline degradation by P. putida 86. Involved in bacterial aromatic compounds degradation; High confidence in function and specificity.
     
  0.449
vanB2
Probable vanillate O-demethylase oxidoreductase (Vanillate degradation ferredoxin-like protein). Homology to vanB of P. sp HR199 of 42% (sprot|VANB_PSEUH). The vanillate demethylase (EC:1.14.13.82) consists of two proteins: an oxygenase and an oxygenase reductase (VanA and VanB). This enzyme is involved in the vanillate degradation, a key intermediate in the degradation of lignin. Pfam: Oxidoredutase FAD-binding domain; Oxidoreductase NAD-binding domain; 2Fe-2S iron-sulfur cluster binding domain no signal peptide no TMHs; Family membership.
     
  0.449
azo3772
Hypothetical protein yhiN. TREMBL:Q7NU52: 55% identity, 66% similarity InterPro; IPR001327; FAD_pyr_redox. InterPro; IPR004792; HI0933_like. InterPro; IPR000719; Prot_kinase. InterPro; IPR001100; Pyr_redox InterPro: HI0933-like protein TIGR00275: conserved hypothetical pro Pfam PF03486; HI0933_like Non-secretory protein with no signal peptide (SignalP predicted) No transmembrane helices (TMHMM predicted); Function unclear.
  
     0.427
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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