STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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Experiments
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[Homology]
Score
azo2201Putative nucleotidyltransferase,; Conserved hypothetical protein. (632 aa)    
Predicted Functional Partners:
azo2202
Probable DNA polymerase III, epsilon subunit,23% Identity to TrEMBL;Q8KDK8. Has EXOIII,SMART;SM00479;IPR006054, DnaQ;This family includes a variety of exonuclease proteins, such as ribonuclease T and the epsilon subunit of DNA polymerase III. Ribonuclease T is responsible for the end-turnover of tRNA,and removes the terminal AMP residue from uncharged tRNA. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria, and also exhibits 3' to 5' exonuclease activity.
 
 
  0.983
azo1149
Conserved hypothetical sodium:solute symporter. Homology to to ws0601 of W. succinogenes of 68% (trembl|Q7M9X9). Sodium/substrate symport (or co-transport) is a widespread mechanism of solute transport across cytoplasmic membranes of pro- and eukaryotic cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient. The solutes transported may be sugars, amino acids, nucleosides, inositols, vitamins,urea or anions, depending on the system. InterPro: Sodium:solute s [...]
 
  
 0.880
azo2409
Conserved hypothetical sodium:solute sympoter. Homology to bb3915 of B. bronchiseptica of 57% (trembl|Q7WCM0). Sodium/substrate symport (or co-transport) is a widespread mechanism of solute transport across cytoplasmic membranes of pro- and eukaryotic cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient. The solutes transported may be sugars, amino acids, nucleosides, inositols, vitamins,urea or anions, depending on the system. Tigrfam: sss: SSS sodium so [...]
 
  
 0.868
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
 0.787
gltB
Ferredoxin-dependent glutamate synthase,; Specificity unclear.
    
 0.737
azo1148
Conserved hypothetical membrane protein. Homology to ws0602 of W. succinogenes of 63% (trembl|Q7MSB5(SRS)) no domains predicted no singal peptide 2 TMHs; Conserved hypothetical protein.
 
     0.733
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.729
azo0682
Conserved hypothetical sodium:solute symporter: Homology to an orf of P. aeruginosa of 72% (trembl|Q9APX1). Sodium/substrate symport (or co-transport) is a widespread mechanism of solute transport across cytoplasmic membranes of pro- and eukaryotic cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient. The solutes transported may be sugars, amino acids, nucleosides, inositols, vitamins,urea or anions, depending on the system. InterPro: Sodium:solute sympor [...]
 
  
 0.680
azo0978
Conserved hypothetical sodium:solute symporter. Homology to an orf of R. capsulata of 81% (trembl|O68042). Sodium/substrate symport (or co-transport) is a widespread mechanism of solute transport across cytoplasmic membranes of pro- and eukaryotic cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient. The solutes transported may be sugars, amino acids, nucleosides,inositols, vitamins, urea or anions, depending on the system. Tigrfam: sss: SSS sodium solute [...]
 
  
 0.672
azo0681
Conserved hypothetical membrane protein. Homology to PP2796 of P. putida of 44% (trembl|Q88J53) PF04341,Protein of unknown function, DUF485;IPR007436;This family includes several putative integral membrane proteins. signal peptide 1 TMHs; Conserved hypothetical protein.
 
  
 0.642
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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