STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xdhAXanthine dehydrogenase (subunit A) oxidoreductase protein; High confidence in function and specificity. (508 aa)    
Predicted Functional Partners:
xdhB
Xanthine dehydrogenase (subunit B) InterPro: Aldehyde oxidase and xanthine dehydrogenase C terminus; High confidence in function and specificity.
 0.999
guaD
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
 
  
  0.959
xdhC
Xanthine dehydrogenase protein, probable (chaperone); High confidence in function and specificity.
 
  
 0.958
azo2215
Conserved hypothetical ABC transporter, permease protein. Homology to orf95 of Pseudomonas sp strain ADP of 57% (trembl|Q936X8). Bacterial binding protein-dependent transport systems are multicomponent systems typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families) (IPR001851). Pfam: Branched-chain ammino acid transporter/pe [...]
 
     0.816
azo2216
Probable ABC transporter, permease protein; TREMBL:Q8XXD9: 46% identity, 59% similarity Hypothetical protein MG120 homolog (A65_orf517). Bacterial inner-membrane translocator.The integral inner-membrane proteins translocate the substrate across the membrane. It has been shown [3, 4] that most of these proteins contain a conserved region located about 80 to 100 residues from their C-terminal extremity InterPro:IPR001851; Bac_inmem_transp. Pfam:PF02653; BPD_transp_2 gntP: gluconate transporter TMH's 9 (TMHMM predicted); Specificity unclear; Belongs to the binding-protein-dependent transp [...]
 
     0.814
azo2214
Conserved hypothetical sugar transporter, ATP-binding protein. Homology to orf96 of P. sp strain ADP of 65% (TREMBL:Q936X7). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR sugars. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. Pfam: AAA-ATPase; ABC transporter. no signal peptide. no TMHs; Specificity unclear.
 
     0.813
azo1183
Conserved hypothetical membrane protein. Homology to RS01489 of Ralstonia solanacearum of 50% (trembl|Q8XXJ8(SRS)) Has PF06181:Protein of unknown function (DUF989);This family consists of several hypothetical bacterial proteins of unknown function. no signal peptide 8 TMHs; Conserved hypothetical protein.
 
     0.738
azo1182
Conserved hypothetical protein. Homology to RS01483 of R.solanacearum of 55% (tremble:Q8XXJ2). No domains predicted. No TMHs. No signal peptide.
 
     0.730
iorB
Putative isoquinoline 1-oxidoreductase, beta subunit Homology to iorB of B. diminuta of 34% (sprot|IORB_BREDI). InterPro: Aldehyde oxidase and xanthine dehydrogenase C terminus (IPR000674) Pfam: Aldehyde oxidase and xanthine dehydrogenase signal peptide no TMHs; Family membership.
 
  
  0.727
azo1184
Conserved hypothetical transthyretin. Homology to pa1518 of P. aeruniosa of 62% (sprot|YF18_PSEAE) InterPro: Transthyretin precursor (IPR000895) Pfam: Transthyretin precursor no signal peptide no TMHs; Conserved hypothetical protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
     0.725
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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