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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
xdhCXanthine dehydrogenase protein, probable (chaperone); High confidence in function and specificity. (364 aa)    
Predicted Functional Partners:
xdhB
Xanthine dehydrogenase (subunit B) InterPro: Aldehyde oxidase and xanthine dehydrogenase C terminus; High confidence in function and specificity.
 
  
 0.983
xdhA
Xanthine dehydrogenase (subunit A) oxidoreductase protein; High confidence in function and specificity.
 
  
 0.957
icmF
Probable methylmalonyl-coa mutase protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
    
  0.879
azo2215
Conserved hypothetical ABC transporter, permease protein. Homology to orf95 of Pseudomonas sp strain ADP of 57% (trembl|Q936X8). Bacterial binding protein-dependent transport systems are multicomponent systems typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families) (IPR001851). Pfam: Branched-chain ammino acid transporter/pe [...]
 
     0.836
azo2216
Probable ABC transporter, permease protein; TREMBL:Q8XXD9: 46% identity, 59% similarity Hypothetical protein MG120 homolog (A65_orf517). Bacterial inner-membrane translocator.The integral inner-membrane proteins translocate the substrate across the membrane. It has been shown [3, 4] that most of these proteins contain a conserved region located about 80 to 100 residues from their C-terminal extremity InterPro:IPR001851; Bac_inmem_transp. Pfam:PF02653; BPD_transp_2 gntP: gluconate transporter TMH's 9 (TMHMM predicted); Specificity unclear; Belongs to the binding-protein-dependent transp [...]
 
     0.833
azo2214
Conserved hypothetical sugar transporter, ATP-binding protein. Homology to orf96 of P. sp strain ADP of 65% (TREMBL:Q936X7). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR sugars. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. Pfam: AAA-ATPase; ABC transporter. no signal peptide. no TMHs; Specificity unclear.
 
     0.831
iorA
Probable isoquinoline 1-oxidoreductase, alpha subunit Homology to iroA of B. diminuta of 58% (sprot|IORA_BREDI). InterPro: [2Fe-2S] binding domain (IPR002888); Ferredoxin (IPR001041) Pfam: 2FE-2S iron-sulfur cluster binding domein, [2Fe-2S] binding domain no signal peptide no TMHs; Specificity unclear.
 
  
 0.808
guaD
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
 
    0.804
azo1183
Conserved hypothetical membrane protein. Homology to RS01489 of Ralstonia solanacearum of 50% (trembl|Q8XXJ8(SRS)) Has PF06181:Protein of unknown function (DUF989);This family consists of several hypothetical bacterial proteins of unknown function. no signal peptide 8 TMHs; Conserved hypothetical protein.
 
    0.756
azo0024
Conserved hypothetical protein; Purine catabolism protein pucB. TREMBL:Q8XZ0: 40% identity, 47% similarity Required for xanthine dehydrogenase activity. Could be involved in formation of the molybdenum cofactor required by xanthine dehydrogenase. FUNCTION: Links a guanosine 5'-phosphate to molydopterin (MPT) forming molybdopterin guanine dinucleotide (MGD) (By similarity). PATHWAY: Molybdenum cofactor biosynthesis. SUBCELLULAR LOCATION: Cytoplasmic (By similarity). SIMILARITY: Belongs to the mobA family. Pfam:UPF0007:Uncharacterized protein family UPF000 ispD: 4-diphosphocytidyl-2C-met [...]
 
  
 0.748
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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