STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2215Conserved hypothetical ABC transporter, permease protein. Homology to orf95 of Pseudomonas sp strain ADP of 57% (trembl|Q936X8). Bacterial binding protein-dependent transport systems are multicomponent systems typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families) (IPR001851). Pfam: Branched-chain ammino acid transporter/pe [...] (354 aa)    
Predicted Functional Partners:
azo2214
Conserved hypothetical sugar transporter, ATP-binding protein. Homology to orf96 of P. sp strain ADP of 65% (TREMBL:Q936X7). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR sugars. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. Pfam: AAA-ATPase; ABC transporter. no signal peptide. no TMHs; Specificity unclear.
 
 
 0.998
azo2216
Probable ABC transporter, permease protein; TREMBL:Q8XXD9: 46% identity, 59% similarity Hypothetical protein MG120 homolog (A65_orf517). Bacterial inner-membrane translocator.The integral inner-membrane proteins translocate the substrate across the membrane. It has been shown [3, 4] that most of these proteins contain a conserved region located about 80 to 100 residues from their C-terminal extremity InterPro:IPR001851; Bac_inmem_transp. Pfam:PF02653; BPD_transp_2 gntP: gluconate transporter TMH's 9 (TMHMM predicted); Specificity unclear; Belongs to the binding-protein-dependent transp [...]
 
 0.998
bmpA
Probable lipoprotein; Description:abc transporter periplasmic binding protein.This is a family of basic membrane lipoproteins from Borrelia and various putative lipoproteins from other bacteria. All of these proteins are outer membrane proteins and are thus antigenic in nature when possessed by the pathogenic members of the family Probable CD4+ T cell-stimulating antigen precursor. TREMBL: Q8XXD8: 64% identity, 79% similarity InterPro:IPR003760; Bmp. Pfam: PF02608; Bmp Secretory protein with high signal peptide probablity (Signal P predicted). No. of transmembrane helices: 1 (TMHMM pre [...]
 
 
 0.959
xdhC
Xanthine dehydrogenase protein, probable (chaperone); High confidence in function and specificity.
 
     0.837
xdhA
Xanthine dehydrogenase (subunit A) oxidoreductase protein; High confidence in function and specificity.
 
     0.816
xdhB
Xanthine dehydrogenase (subunit B) InterPro: Aldehyde oxidase and xanthine dehydrogenase C terminus; High confidence in function and specificity.
 
     0.814
cbiQ
Putative cobalt transport system permease protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Similar to the cobalt transport membrane protein, CbiQ in A. pleuropneumoniae; Function unclear.
 
     0.501
cbiM
Putative cobalt transport system, permease protein; Part of the ABC transporter complex cbiKMQO involved in cobalt import. Similar to the cobalt transport membrane protein, CbiM in A. pleuropneumoniae. InterPro: Cobalamin synthesis CBIM cbiM: cobalamin biosynthesis protein Cbi; High confidence in function and specificity.
 
     0.494
guaD
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
 
     0.459
pyrD
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
       0.438
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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