STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2229Conserved hypothetical secreted protein. Homology to PSPTO5169 of P.syringae 45% (tremble:Q87UX3). No domains predicted. Signal P reporting Signal Peptide present. No TMH being reported as present; Conserved hypothetical protein. (82 aa)    
Predicted Functional Partners:
waaP2
Lipopolysaccharide core biosynthesis protein rfaP. INVOLVED IN ATTACHMENT OF PHOSPHATE-CONTAINING SUBSTITUENTS TO THE INNER CORE. Specific function unclear.
  
     0.705
azo3206
Membrane protein, alkaline phosphatase superfamily.
  
     0.663
waaP3
Lipopolysaccharide core biosynthesis protein. INVOLVED IN ATTACHMENT OF PHOSPHATE-CONTAINING SUBSTITUENTS TO THE INNER CORE. Specific function unclear.
  
     0.634
colS
Two-component system sensor protein ColS,; High confidence in function and specificity.
  
     0.611
inaA
Conserved hypothetical InaA protein. Homology to inaA of P. putida of 39% (gnl|keqq|ppu:PP0904(KEGG)). Pfam: Lipopolysaccharide kinase (Kdo/WaaP) family. These lipopolysaccharide kinases are related to protein kinases Pkinase. This family includes waaP (rfaP) gene product is required for the addition of phosphate to O-4 of the first heptose residue of the lipopolysaccharide (LPS) inner core region. It has previously been shown that WaaP is necessary for resistance to hydrophobic and polycationic antimicrobials in E. coli and that it is required for virulence in invasive strains of S. e [...]
  
     0.576
azo3571
Conserved hypothetical protein; InterPro: Eukaryotic protein kinase. Might be related to lipopolysaccharide biosynthesis, due to the presence of the gene in a lipopolysaccharide gene cluster.
  
     0.567
azo3160
Conserved hypothetical protein; Similar to TREMBL:P95473 (66% identity); TREMBL:Q87X18 (66% identity); TREMBL:Q87TV0 (61% identity).
  
     0.556
azo1728
Conserved hypothetical secreted protein; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family.
  
     0.542
azo2254
Conserved hypothetical secreted protein. Homology to PP2811 of P.putida of 32% (tremble:Q88J38). Has PF06980;Protein of unknown function (DUF1302)domain;IPR010727 This family contains a number of hypothetical bacterial proteins of unknown function that are approximately 600 residues long. Most family members seem to be from Pseudomonas. Signal peptide present. No TMH reported; Conserved hypothetical protein.
  
     0.522
azo2226
Probable N-acetylmuramoyl-L-alanine amidase amiA precursor, 28% identity to TrEMBL;Q823N1. 26% identity to SwissProt;P36548 Has SMART;SM00646, Ami_3. Signal Peptide present. Has PF01520; N-acetylmuramoyl-L-alanine amidase; IPR002508 Amidase_3_hydro; This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls.
       0.505
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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