STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
udgHPutative UDP-glucose 6-dehydrogenase; 61% UDPG_MGDP_dh. Pfam:PF00984; UDPG_MGDP_dh; 1.PF03720; UDPG_MGDP_dh_C; 1.PF03721; UDPG_MGDP_dh_N; 1. Signal peptide: present; High confidence in function and specificity. (440 aa)    
Predicted Functional Partners:
rmlA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 
 0.924
gumJ
Putative polysaccharide translocase; 25% Polysacc_synt. Pfam:PF01943; Polysacc_synt; 1. TMhelix:14. Non-secretory protein; Family membership.
  
  
 0.886
galU
UTP--glucose-1-phosphate uridylyltransferase 1 (EC 2.7.7.9) (UDP- glucose pyrophosphorylase 1) (UDPGP 1) (Alpha-D-glucosyl-1-phosphate uridylyltransferase 1) (Uridine diphosphoglucose pyrophosphorylase 1). InterPro: ADP-glucose pyrophosphorylase ispD: 4-diphosphocytidyl-2C-methyl-D-er; High confidence in function and specificity.
  
 0.871
rmlC
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
 
 0.855
xanB
Probable xanthan biosynthesis protein XanB. Homology to xanB of X. campestris of 60% (sprot|XANB_XANCP(SRS)) Xanthan biosynthesis protein XanB is a multifunctional enzyme including Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphomannose isomerase) (PMI) (Phosphohexomutase)and Mannose-1-phosphate guanylyl transferase (GDP) (EC 2.7.7.22) (GDP-mannose pyrophosphorylase) (GMP). InterPro: ADP-glucose pyrophosphorylase (IPR005835); Mannose-6-phosphate isomerase type II (IPR001538) Pfam: Nucleotidyl transferase, Mannose-6-phosphate isomerase no signal peptide no TMHs; Family membership.
 
 
 0.853
rmlB
dTDP-glucose 46-dehydratase (EC 4.2.1.46). InterPro: NAD dependent epimerase/dehydratase family; High confidence in function and specificity; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
 
 0.846
azo2231
Putative Mannose-1-phosphate guanylyltransferase; Mannose-1-phosphate guanyltransferase involved in the reaction:GTP + alpha-D-mannose 1-phosphate = diphosphate + GDPmannose. 51% Hexapep_transf.IPR005835; NTP_transferase. Pfam:PF00132; Hexapep; 2.PF00483; NTP_transferase; 1; High confidence in function and specificity.
  
 
 0.783
wbnF
Putative nucleotide sugar epimerase; Probably involved in the biosynthesis of exopolysaccharides. 68% Epimerase_Dh.IPR008089; Nuc_sugar_epim. Pfam:PF01370; Epimerase; 1; High confidence in function and specificity.
 
 0.736
azo3256
Conserved hypothetical polysaccharide biosynthesis protein, related to GumJ. Homology to ebA4295 of Azoarcus sp. EbN1 of 42%. Pfam: Polysaccharide biosynthesis protein. Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide. The family includes RfbX part of the O antigen biosynthesis operon. The family includes SpoVB from Bacillus subtilis SP5B_BACSU, which is involved in spore cortex biosynthesis. No signal peptide. 10 TMHs; Family membership.
  
  
 0.734
gumM
Putative glycosyltransferase; 60% WecB_TagA_CpsF. Pfam:PF03808; Glyco_tran_WecB; 1. TIGRFAMs:TIGR00696; wecB_tagA_cpsF; 1. Non-secretory protein; High confidence in function and specificity; Belongs to the glycosyltransferase 26 family.
     
 0.691
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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