Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gumJPutative polysaccharide translocase; 25% Polysacc_synt. Pfam:PF01943; Polysacc_synt; 1. TMhelix:14. Non-secretory protein; Family membership. (490 aa)    
Predicted Functional Partners:
gumD
Putative glycosyltransferase; 43% Bact_transf. Pfam:PF02397; Bac_transf; 1. TMhelix:5; Specificity unclear.
 
  
 0.934
azo3193
Glycosyltransferase; Might transfer a sugar moiety directly to a lipd acceptor. Putative colanic biosynthesis UDP-glucose lipid carrier transferase. InterPro: Bacterial sugar transferase; Family membership.
 
  
 0.930
udgH
Putative UDP-glucose 6-dehydrogenase; 61% UDPG_MGDP_dh. Pfam:PF00984; UDPG_MGDP_dh; 1.PF03720; UDPG_MGDP_dh_C; 1.PF03721; UDPG_MGDP_dh_N; 1. Signal peptide: present; High confidence in function and specificity.
  
  
 0.886
rmlB
dTDP-glucose 46-dehydratase (EC 4.2.1.46). InterPro: NAD dependent epimerase/dehydratase family; High confidence in function and specificity; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.880
rmlC
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
  
 0.878
rmlA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
  
 0.878
gumM
Putative glycosyltransferase; 60% WecB_TagA_CpsF. Pfam:PF03808; Glyco_tran_WecB; 1. TIGRFAMs:TIGR00696; wecB_tagA_cpsF; 1. Non-secretory protein; High confidence in function and specificity; Belongs to the glycosyltransferase 26 family.
 
  
 0.845
azo3256
Conserved hypothetical polysaccharide biosynthesis protein, related to GumJ. Homology to ebA4295 of Azoarcus sp. EbN1 of 42%. Pfam: Polysaccharide biosynthesis protein. Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide. The family includes RfbX part of the O antigen biosynthesis operon. The family includes SpoVB from Bacillus subtilis SP5B_BACSU, which is involved in spore cortex biosynthesis. No signal peptide. 10 TMHs; Family membership.
  
   
 0.804
gumK
Putative glucuronyl transferase; 64%; High confidence in function and specificity.
  
 
 0.744
ugd
UDP-glucose 6-dehydrogenase (EC 1.1.1.22) (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH); High confidence in function and specificity.
  
  
 0.734
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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