STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gumBPutative capsule polysaccharide export protein precursor.May be involved in polysaccharide polymerization or transport. 36% Poly_export. Pfam:PF02563; Poly_export; 1. Signal peptide: present; Family membership. (269 aa)    
Predicted Functional Partners:
gumC
Putative exopolysaccharide biosynthesis protein; 21% LPS_Wzz_MPA. Pfam:PF02706; Wzz; 1. TMhelix:1. Signal peptide:present; High confidence in function and specificity.
 
 0.994
gumD
Putative glycosyltransferase; 43% Bact_transf. Pfam:PF02397; Bac_transf; 1. TMhelix:5; Specificity unclear.
 
 
 0.991
azo3193
Glycosyltransferase; Might transfer a sugar moiety directly to a lipd acceptor. Putative colanic biosynthesis UDP-glucose lipid carrier transferase. InterPro: Bacterial sugar transferase; Family membership.
 
 
 0.981
wzc1
Tyrosine-protein kinase wzc (EC 2.7.10.1). Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium (By similarity). gidA: glucose-inhibited division prot; High confidence in function and specificity.
 
 0.967
azo3282
Conserved hypothetical polysaccharide chain length determinant protein. Homology to ebA4249 of Azoarcus sp. EbN1 of 66%. No signal peptide. 3 TMHS. Pfam: Wzz = Chain length determinant protein. This family includes proteins involved in lipopolysaccharide (lps) biosynthesis. This family comprises the whole length of chain length determinant protein (or wzz protein) that confers a modal distribution of chain length on the O-antigen component of lps. This region is also found as part of bacterial tyrosine kinases such as ETK_ECOLI; Family membership.
 
 0.938
azo2243
Conserved hypothetical secreted protein. Homology to TdenA01000001 of Thiobacillus denitrificans of 33% (gi|52007706|ref|ZP_00335083.1|(NBCI ENTREZ)). no domains predicted. signal peptide. no TMHs; Conserved hypothetical protein.
 
     0.904
wzc2
Putative tyrosine-protein kinase (EC 2.7.10.1); High confidence in function and specificity.
 
 0.902
azo2245
Hypothetical secreted protein. No good homology to the data bank. No domains predicted. No TMHs. Signal peptide present.
 
  
  0.894
wza
Conserved hypothetical polysaccharid export protein. Homology to wza of Azoarcus sp. EbN1 of 80%. Pfam: Polysaccharide biosynthesis/export protein. This is a family of periplasmic proteins involved in polysaccharide biosynthesis and/or export. No TMHs. Signal peptide present., ; Family membership.
  
  
 
0.826
gumF
Putative acetyltransferase; 44% Acyl_transf_3. Pfam:PF01757; Acyl_transf_3; 1. TMhelix:9. Non-secretory protein; High confidence in function and specificity.
  
  
 0.768
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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