| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo2268 | azo2269 | azo2268 | azo2269 | Conserved hypothetical membrane protein. Homology to pp4833 of P. putida of 55% (trembl|Q88DJ2). no domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein. | Conserved hypothetical band 7 family protein. Homology to pp4834 of P.putida of 67% (trembl|Q88DJ1). InterPro: Band 7 protein (IPR001107). Pfam: SPFH domain / Band 7 family. The band 7 protein is an integral membrane protein which is thought to regulate cation conductance. A variety of proteins belong to this family. These include the prohibitins, cytoplasmic anti-proliferative proteins and stomatin, an erythrocyte membrane protein. Bacterial HflC protein also belongs to this family. probable 1 TMH. probable signal peptide (overlapping with the TMH); Family membership. | 0.981 |
| azo2268 | azo3571 | azo2268 | azo3571 | Conserved hypothetical membrane protein. Homology to pp4833 of P. putida of 55% (trembl|Q88DJ2). no domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein. | Conserved hypothetical protein; InterPro: Eukaryotic protein kinase. Might be related to lipopolysaccharide biosynthesis, due to the presence of the gene in a lipopolysaccharide gene cluster. | 0.501 |
| azo2268 | azo3757 | azo2268 | azo3757 | Conserved hypothetical membrane protein. Homology to pp4833 of P. putida of 55% (trembl|Q88DJ2). no domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein. | Modification methylase TaqI (EC 2.1.1.72) (Adenine-specific methyltransferase TaqI) (M.TaqI). THIS METHYLASE RECOGNIZES THE DOUBLE-STRANDED SEQUENCE TCGA CAUSES SPECIFIC METHYLATION ON A-4 ON BOTH STRANDS AND PROTECTS THE DNA FROM CLEAVAGE BY THE TAQI ENDONUCLEASE. InterPro: N6 adenine-specific DNA methyltransferase N12 class; Family membership. | 0.533 |
| azo2268 | cbiH | azo2268 | azo3537 | Conserved hypothetical membrane protein. Homology to pp4833 of P. putida of 55% (trembl|Q88DJ2). no domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein. | Precorrin-3B C17- methyltransferase. METHYLTRANSFERASE THAT CATALYZES THE METHYLATION OF C-17 IN PRECORRIN-3B TO FORM PRECORRIN-4 (BY SIMILARITY). InterPro: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; High confidence in function and specificity. | 0.500 |
| azo2268 | cdsA | azo2268 | azo1904 | Conserved hypothetical membrane protein. Homology to pp4833 of P. putida of 55% (trembl|Q88DJ2). no domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein. | Phosphatidate cytidylyltransferase :- catalytic activity ctp + phosphatidate = diphosphate + cdp-diacylglycerol. pathway :-phospholipid biosynthesis. Entry name:- CDSA_ECOLI Primary accession number :- P06466 InterPro:- IPR000374; PC_trans. Identities = 89/252 (35%) Pfam PF01148; CTP_transf_1; 1. Number of predicted TMHs: 7 Prediction: Signal peptide Signal peptide probability: 1.0; Family membership; Belongs to the CDS family. | 0.485 |
| azo2268 | cobQ | azo2268 | azo3517 | Conserved hypothetical membrane protein. Homology to pp4833 of P. putida of 55% (trembl|Q88DJ2). no domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.491 |
| azo2268 | cobS | azo2268 | azo3561 | Conserved hypothetical membrane protein. Homology to pp4833 of P. putida of 55% (trembl|Q88DJ2). no domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein. | Cobalamin (5'-phosphate) synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.854 |
| azo2268 | gstB | azo2268 | azo2267 | Conserved hypothetical membrane protein. Homology to pp4833 of P. putida of 55% (trembl|Q88DJ2). no domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein. | Probable Glutathione transferase. Homology to gstB of P. mirablilis of 29% (sprot|GT_PROMI). Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. InterPro: Glutathione S-transferase N terminus(IPR004045), Glutathione S-transferase C terminus (IPR004046) Pfam: Glutathione S-transferase, N-terminale domaine no signal peptide no TMHs; Family membership. | 0.470 |
| azo2268 | hflC | azo2268 | azo0935 | Conserved hypothetical membrane protein. Homology to pp4833 of P. putida of 55% (trembl|Q88DJ2). no domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein. | Conserved hypothetical protein HflC; HflC and HflK could regulate a protease. | 0.622 |
| azo2268 | hflK | azo2268 | azo0934 | Conserved hypothetical membrane protein. Homology to pp4833 of P. putida of 55% (trembl|Q88DJ2). no domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein. | Putative Hflk protein; HflC and HflK could encode or regulate a protease. | 0.571 |
| azo2269 | azo2268 | azo2269 | azo2268 | Conserved hypothetical band 7 family protein. Homology to pp4834 of P.putida of 67% (trembl|Q88DJ1). InterPro: Band 7 protein (IPR001107). Pfam: SPFH domain / Band 7 family. The band 7 protein is an integral membrane protein which is thought to regulate cation conductance. A variety of proteins belong to this family. These include the prohibitins, cytoplasmic anti-proliferative proteins and stomatin, an erythrocyte membrane protein. Bacterial HflC protein also belongs to this family. probable 1 TMH. probable signal peptide (overlapping with the TMH); Family membership. | Conserved hypothetical membrane protein. Homology to pp4833 of P. putida of 55% (trembl|Q88DJ2). no domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein. | 0.981 |
| azo2269 | gstB | azo2269 | azo2267 | Conserved hypothetical band 7 family protein. Homology to pp4834 of P.putida of 67% (trembl|Q88DJ1). InterPro: Band 7 protein (IPR001107). Pfam: SPFH domain / Band 7 family. The band 7 protein is an integral membrane protein which is thought to regulate cation conductance. A variety of proteins belong to this family. These include the prohibitins, cytoplasmic anti-proliferative proteins and stomatin, an erythrocyte membrane protein. Bacterial HflC protein also belongs to this family. probable 1 TMH. probable signal peptide (overlapping with the TMH); Family membership. | Probable Glutathione transferase. Homology to gstB of P. mirablilis of 29% (sprot|GT_PROMI). Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. InterPro: Glutathione S-transferase N terminus(IPR004045), Glutathione S-transferase C terminus (IPR004046) Pfam: Glutathione S-transferase, N-terminale domaine no signal peptide no TMHs; Family membership. | 0.492 |
| azo2269 | hflC | azo2269 | azo0935 | Conserved hypothetical band 7 family protein. Homology to pp4834 of P.putida of 67% (trembl|Q88DJ1). InterPro: Band 7 protein (IPR001107). Pfam: SPFH domain / Band 7 family. The band 7 protein is an integral membrane protein which is thought to regulate cation conductance. A variety of proteins belong to this family. These include the prohibitins, cytoplasmic anti-proliferative proteins and stomatin, an erythrocyte membrane protein. Bacterial HflC protein also belongs to this family. probable 1 TMH. probable signal peptide (overlapping with the TMH); Family membership. | Conserved hypothetical protein HflC; HflC and HflK could regulate a protease. | 0.693 |
| azo3571 | azo2268 | azo3571 | azo2268 | Conserved hypothetical protein; InterPro: Eukaryotic protein kinase. Might be related to lipopolysaccharide biosynthesis, due to the presence of the gene in a lipopolysaccharide gene cluster. | Conserved hypothetical membrane protein. Homology to pp4833 of P. putida of 55% (trembl|Q88DJ2). no domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein. | 0.501 |
| azo3757 | azo2268 | azo3757 | azo2268 | Modification methylase TaqI (EC 2.1.1.72) (Adenine-specific methyltransferase TaqI) (M.TaqI). THIS METHYLASE RECOGNIZES THE DOUBLE-STRANDED SEQUENCE TCGA CAUSES SPECIFIC METHYLATION ON A-4 ON BOTH STRANDS AND PROTECTS THE DNA FROM CLEAVAGE BY THE TAQI ENDONUCLEASE. InterPro: N6 adenine-specific DNA methyltransferase N12 class; Family membership. | Conserved hypothetical membrane protein. Homology to pp4833 of P. putida of 55% (trembl|Q88DJ2). no domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein. | 0.533 |
| cbiH | azo2268 | azo3537 | azo2268 | Precorrin-3B C17- methyltransferase. METHYLTRANSFERASE THAT CATALYZES THE METHYLATION OF C-17 IN PRECORRIN-3B TO FORM PRECORRIN-4 (BY SIMILARITY). InterPro: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; High confidence in function and specificity. | Conserved hypothetical membrane protein. Homology to pp4833 of P. putida of 55% (trembl|Q88DJ2). no domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein. | 0.500 |
| cbiH | cobQ | azo3537 | azo3517 | Precorrin-3B C17- methyltransferase. METHYLTRANSFERASE THAT CATALYZES THE METHYLATION OF C-17 IN PRECORRIN-3B TO FORM PRECORRIN-4 (BY SIMILARITY). InterPro: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; High confidence in function and specificity. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.993 |
| cbiH | cobS | azo3537 | azo3561 | Precorrin-3B C17- methyltransferase. METHYLTRANSFERASE THAT CATALYZES THE METHYLATION OF C-17 IN PRECORRIN-3B TO FORM PRECORRIN-4 (BY SIMILARITY). InterPro: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; High confidence in function and specificity. | Cobalamin (5'-phosphate) synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.936 |
| cdsA | azo2268 | azo1904 | azo2268 | Phosphatidate cytidylyltransferase :- catalytic activity ctp + phosphatidate = diphosphate + cdp-diacylglycerol. pathway :-phospholipid biosynthesis. Entry name:- CDSA_ECOLI Primary accession number :- P06466 InterPro:- IPR000374; PC_trans. Identities = 89/252 (35%) Pfam PF01148; CTP_transf_1; 1. Number of predicted TMHs: 7 Prediction: Signal peptide Signal peptide probability: 1.0; Family membership; Belongs to the CDS family. | Conserved hypothetical membrane protein. Homology to pp4833 of P. putida of 55% (trembl|Q88DJ2). no domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein. | 0.485 |
| cobQ | azo2268 | azo3517 | azo2268 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Conserved hypothetical membrane protein. Homology to pp4833 of P. putida of 55% (trembl|Q88DJ2). no domains predicted. no signal peptide. 2 TMHs; Conserved hypothetical protein. | 0.491 |