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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
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azo2275Putative glutamine amidotransferase; Hypothetical protein ycjL. TREMBL:Q890B8: 38% identity, 53% similarity. Glutamine amidotransferase activity involves the removal of the ammonia group from a glutamate molecule and its subsequent transfer to a pecific substrate, thus creating a new carbon-nitrogen group on the substrate. InterPro:IPR000991; GATase_1 PROSITE PS00442 GATASE_TYPE_I BLOCKS: BL00442 PFAM:PF00117 GATase; PF00310 GATase_2 trpG_papA: glutamine amidotransferase o No signal peptide (SignalP predicted) No transmembrane helices; High confidence in function and specificity. (262 aa)    
Predicted Functional Partners:
ybdK
Glutamate-cysteine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     0.930
gltB
Ferredoxin-dependent glutamate synthase,; Specificity unclear.
    
  0.895
azo2277
Conserved hypothetical Na/H antiporter. Homology to Bucepa03004091 of B.cepacia of 41% (gi|46320868|ref|ZP_00221251.1|(NBCI ENTREZ)). Has PF00999 Sodium/hydrogen exchanger family; IPR006153. Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserv [...]
 
     0.871
putA
Probable bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
     
  0.871
glnA
Glutamine synthetase I (GS) plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine. Similar to pir|G83005 (70%) and to pir|AJECQ (66%). Pfam (PF00120): Glutamine synthetase, catalytic domain Pfam (PF03951): Glutamine synthetase, beta-Grasp domain; High confidence in function and specificity.
  
 
 0.743
glnT
Glutamine synthetase III plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine. Similar to trembl|Q98A06 (58%) and to sprot|GLN3_RHILP (38%). Pfam (PF03951): Glutamine synthetase, beta-Grasp domain Pfam(PF00120): Glutamine synthetase, catalytic domain; High confidence in function and specificity.
  
 
 0.743
ordL
This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase,Sarcosine oxidase beta subunit, D-alanine oxidase, D-aspartate oxidase. Similar to trembl|Q88AY5 (61%) and to sprot|ORDL_ECOLI (32%). Pfam (PF01266): D-amino acid oxidase ProSite (PS50205): NAD binding site; Family membership.
 
  
 0.723
trpD
1,4-alpha-glucan branching enzyme; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
     
  0.626
gltD
Glutamate synthase (small chain) oxidoreductase; Glutamate synthase [NADPH] precursor (EC 1.4.1.13) (NADPH-GOGAT)small chain. TREMBL:Q8XV67-77% identity, 87% similarity InterPro:IPR006005- One pathway for the assimilation of ammonia and glutamate biosynthesis involves glutamate synthase (EC: 1.4.1.13) which transfers the amide group of glutamine to 2-oxoglutarate to yield two molecules of glutamate. 2 L-glutamate + NADP+ = L-glutamine + 2-oxoglutarate + NADPH + H+ gid: gid protein Pfam:FAD binding domain,Thi family, 4Fe-4S binding domain,KTN-NAD binding domain, DUF127; High confidence [...]
    
 0.512
azo3076
Conserved hypothetical protein. Homology to TdenA01001814 of Thiobacillus denitrificans of 40% (gi|52006871|ref|ZP_00334250.1|(NBCI ENTREZ)). Has PF01402, Ribbon-helix-helix protein, copG family; IPR002145 HTH_CopG; The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerisation and not DNA binding as might have been expected. No TMHs. No signal peptide.
     
  0.505
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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