STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ybdKGlutamate-cysteine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (375 aa)    
Predicted Functional Partners:
azo2277
Conserved hypothetical Na/H antiporter. Homology to Bucepa03004091 of B.cepacia of 41% (gi|46320868|ref|ZP_00221251.1|(NBCI ENTREZ)). Has PF00999 Sodium/hydrogen exchanger family; IPR006153. Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserv [...]
 
     0.942
gshB
Glutathione synthetase (GSH synthetase) (GSH-S) (GSHase). InterPro: Prokaryotic glutathione synthetase ATP-binding domain; High confidence in function and specificity; Belongs to the prokaryotic GSH synthase family.
    
 0.936
azo2275
Putative glutamine amidotransferase; Hypothetical protein ycjL. TREMBL:Q890B8: 38% identity, 53% similarity. Glutamine amidotransferase activity involves the removal of the ammonia group from a glutamate molecule and its subsequent transfer to a pecific substrate, thus creating a new carbon-nitrogen group on the substrate. InterPro:IPR000991; GATase_1 PROSITE PS00442 GATASE_TYPE_I BLOCKS: BL00442 PFAM:PF00117 GATase; PF00310 GATase_2 trpG_papA: glutamine amidotransferase o No signal peptide (SignalP predicted) No transmembrane helices; High confidence in function and specificity.
     0.930
azo1514
Conserved hypothetical protein. Homology to RS04633 of R.solanacearum of 73% (tremble:Q8Y0C3). Has PF04169(IPR007297);Domain of unknown function (DUF404);This is a protein of unknown function. It sometimes occurs in combination with two domains of unknown function DUF403 (IPR007296) and DUF407 (IPR007302). Has PF04174;Domain of unknown function (DUF407);This is a protein of unknown function. It sometimes occurs in combination with two domains of unknown function DUF403 (IPR007296) and DUF404 (IPR007297). No signal Peptide or TMH present.
   
  0.895
gltB
Ferredoxin-dependent glutamate synthase,; Specificity unclear.
     
  0.888
gshA
GshA protein; Glutamate--cysteine ligase. Glutathione metabolism; High confidence in function and specificity.
  
  
  0.874
pepA
Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
  0.870
pepD
Probable aminoacyl-histidine dipeptidase (EC 3.4.13.3) (Xaa-His dipeptidase) (X-His dipeptidase) (Beta-alanyl-histidine dipeptidase) (Carnosinase) (Peptidase D). Homology to pepD of E. coli of 44%. THIS DIPEPTIDASE HAS SPECIFICITY FOR THE UNUSUAL DIPEPTIDE BETA-ALANYL-L-HISTIDINE. InterPro: Peptidase family M20/M25/M40 (IPR002933) Pfam: Peptidase family M20/M25/M40 no signal peptide no TMHs; High confidence in function and specificity.
     
  0.855
cysK
Cysteine synthase A,; High confidence in function and specificity; Belongs to the cysteine synthase/cystathionine beta- synthase family.
     
  0.855
pepN
PepN protein; Aminopeptidase catalyzes the removal of single amino acids from the amino terminus of small peptides and probable plays a role in their final digestion. Similar to trembl|Q8XXI8 (50%) and to sprot|AMPN_ECOLI (47%). Pfam (PF01433): Aminopeptidase N, APN (CD13); Specificity unclear.
     
  0.855
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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