STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2277Conserved hypothetical Na/H antiporter. Homology to Bucepa03004091 of B.cepacia of 41% (gi|46320868|ref|ZP_00221251.1|(NBCI ENTREZ)). Has PF00999 Sodium/hydrogen exchanger family; IPR006153. Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserv [...] (402 aa)    
Predicted Functional Partners:
ybdK
Glutamate-cysteine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
 
     0.940
azo2275
Putative glutamine amidotransferase; Hypothetical protein ycjL. TREMBL:Q890B8: 38% identity, 53% similarity. Glutamine amidotransferase activity involves the removal of the ammonia group from a glutamate molecule and its subsequent transfer to a pecific substrate, thus creating a new carbon-nitrogen group on the substrate. InterPro:IPR000991; GATase_1 PROSITE PS00442 GATASE_TYPE_I BLOCKS: BL00442 PFAM:PF00117 GATase; PF00310 GATase_2 trpG_papA: glutamine amidotransferase o No signal peptide (SignalP predicted) No transmembrane helices; High confidence in function and specificity.
 
     0.872
azo2611
Conserved hypothetical membrane protein. Homology to rs00511 of R. solanacearum of 32% (trembl|Q8XUW6(SRS)). No domains predicted. singal peptide. 2 TMHs; Conserved hypothetical protein.
  
     0.639
azo3151
Conserved hypothetical protein. Homology to ebA7126 of Azoarcus sp. EbN1 of 45% (gnl|keqq|eba:ebA7126(KEGG)). No domains predicted. No TMHs. No signal peptide.
  
     0.635
azo3634
Probable D-(-)-3-hydroxybutyrate oligomer hydrolase; Participates in the degradation of poly-3-hydroxybutyrate (PHB). It works downstream of poly(3-hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB- oligomers) into 3HB-monomers; Belongs to the D-(-)-3-hydroxybutyrate oligomer hydrolase family.
  
     0.582
azo0282
Conserved hypothetical protein. Homology to RS03060 of R.solanacearum of 35% (tremble:Q8XQ03) No domains predicted. No signal peptide or TMH present.
  
     0.550
azo0152
Conserved hypothetical membrane protein. Homology to BB4612 of Bordetella bronchiseptica of 37% (trembl|Q7WEM2(SRS)). No domains predicted. signal peptide 3 TMHs; Conserved hypothetical protein.
  
     0.519
azo2763
Conserved hypothetical secreted protein. Homology to ebA945 of Azoarcus sp. EbN1 of 47% (gnl|keqq|eba:ebA945(KEGG)). No domains predicted. Signal P reporting signal peptide present. No TMH present; Conserved hypothetical protein.
  
     0.494
sbp1
Sulfate-binding protein precursor, Sbp. E.coli Sulfate starvation-induced protein 2,SSI2. This protein specifically binds sulfate and is involved in its transmembrane transport. InterPro: Prokaryotic sulfate-/thiosulfate-binding protein. In other bacteria Sbp is a periplasmic component of an ABC transport system. TIGR00363: lipoprotein YaeC family Signal peptide; High confidence in function and specificity.
       0.488
azo0279
Conserved hypothetical protein. Homology to BB1132 of B.bronchiseptica of 42% (tremble:Q7WNA8). No domains predicted. No Signal peptide or TMH present.
  
     0.474
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.