Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo2283Conserved hypothetical protein; Similar to TREMBL:Q92PT6 (40% identical); TREMBL:Q98MM5 (39% identical). (216 aa)    
Predicted Functional Partners:
chrR
Probable chromate reductase. Homology to chrR of E. coli of 49% (tremblnew|AAK62985). Reduction of chromate (Cr(VI)) to Cr(III).no no signal peptide no TMHs; High confidence in function and specificity.
 
    0.676
azo0525
Conserved hypothetical protein. Homology to an orf of P. stuzeri of 49% (trembl|Q93JV4). Tigrfam: arsC: arsenate reductase. Pfam: ArsC family (PF03960) no signal peptide. no TMHs.
    
 
 0.568
azo1658
Putative arsenate reductase protein; 45% Arsen_reductase.IPR006504; Cons_hypoth_ArsC. Pfam:PF03960; ArsC; 1. ArsC:arsenate reductase, catalyzes the reduction of arsenate to arsenite. Probably involved in arsenic resistance; High confidence in function and specificity.
    
 
 0.568
azo2067
Arsenate reductase (EC 1.20.4.1) (Arsenical pump modifier). REDUCTION OF ARSENATE [AS(V)] TO ARSENITE [AS(III)]. THIS PROTEIN EXPANDS THE SUBSTRATE SPECIFICITY OF ARSAB PUMP WHICH CAN EXTRUDE ARSENITE AND ANTIMONITE TO ALLOW FOR ARSENATE PUMPING AND RESISTANCE. arsC: arsenate reductase; High confidence in function and specificity.
    
 
 0.568
azo2282
Conserved hypothetical protein. Identity to Daro_1071 of Dechloromonas aromatica of 41% (gi|71846331|gb|AAZ45827.1|). Pfam: CheW-like domain. CheW-like domain proteins are part of the chemotaxis signaling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and other related proteins that are involved in chemotaxis. The CheW-like regulatory domain in CheA binds to CheW, suggesting that these domains can interact with each other.
       0.563
flgD
Probable basal-body rod modification protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein.
    
   0.536
flgC
Flagellar basal-body rod protein flgC. The rod has been shown to consist of four different, yet evolutionary related proteins: in the distal portion of the rod there are about 26 subunits of protein flgG and in the proximal portion there are about six subunits each of proteins flgB, flgC, and flgF. These four proteins contain a highly conserved asparagine-rich domain at their N terminus. InterPro: Flagella basal body rod protein no signal peptide no TMHs; High confidence in function and specificity.
    
   0.536
dsbA
Putative protein disulfide-isomerase. Homology to dsbA of P. flourescens of 34%. Involved in disulfide-bond formation. Acts by transferring its disulfide bond to other proteins. Tigrfam: redox_disulf_1: redox-active disulfid Pfam: DSBA Oxidoreductase signal peptide no TMHS; Family membership.
    
 0.532
dsbC
Putative protein disulfide-isomerase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
    
 0.532
azo0069
Conserved hypothetical globin-like protein. Homology to rpa2719 of R. palustris of 46% (tremblnew|CAE28161). Interpro: IPR009050 Globin-like. Globins are heme-containing proteins involved in binding and/or transporting oxygen. This family of heme binding proteins are found mainly in bacteria. No signal peptide. No TMHs; Function unclear.
  
  
 0.474
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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