STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2294Putative Zinc carboxypeptidase-related protein, 45% identity to TrEMBL;Q6MKH4,Zinc carboxypeptidase-related protein (EC 3.4.17.-) [Bd2418] [Bdellovibrio bacteriovorus] Has pfam00246, Zn_carbOpept, Zinc carboxypeptidase domain; High confidence in function and specificity. (364 aa)    
Predicted Functional Partners:
azo2295
Putative hydrolase; TREMBL:Q8EFJ6: 33% identity, 47% similarity. Probable Dihydrolipoamide acetyltransferase component of acetoin cleaving system (EC 2.3.1.12) (Acetoin dehydrogenase E2 component). Interpro:IPR000073; A/b_hydrolase (alpha/beta fold family). IPR000379; Ser_estrs. Pfam PF00561; Abhydrolase_1; 1 2a75: L-lysine exporter; Function unclear.
 
     0.926
alkB
DNA-directed DNA polymerase; Alkylated DNA repair protein.Probably involved in the repair of alkylated DNA. Provides extensive resistance to alkylating agents.; High confidence in function and specificity.
       0.548
ada
Methylated-DNA--[protein]-cysteine S-methyltransferase (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase) InterPro: Methylated-DNA--protein-cysteine methyltransferase; High confidence in function and specificity.
       0.529
era
Probable GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
   
 
  0.522
azo0059
Conserved hypothetical secreted protein. Homology to rsc3030 of R. solanacearum of 48% (sprot|YU30_RALSO) Pfam: Alpha-2-macroglobulin family Nterminal region (PF01835, PF07703) signal peptide no TMHs; Conserved hypothetical protein.
    
 0.510
azo2219
Conserved hypothetical membrane protein. Homology to cbiL of Actinobacillus pleuropneumoniae of 39% (gi|5733705|gb|AAD49725.1|(NBCI ENTREZ)). Signal P reproting signal peptide present. TMHMM reporting TMH present; Conserved hypothetical protein.
    
 0.510
rpsE
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
    
  0.489
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.484
azo2300
Conserved hypothetical membrane protein. Homology to ORF428 of Roseateles depolymerans of 65% (trembl|Q9F206(SRS)). Pfam: Protein of unknown function (DUF1504). This family consists of several hypothetical bacterial proteins of around 440 residues in length. The function of this family is unknown. signal peptide. 10 TMHs; Conserved hypothetical protein.
 
     0.446
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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