Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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[Homology]
Score
azo2294Putative Zinc carboxypeptidase-related protein, 45% identity to TrEMBL;Q6MKH4,Zinc carboxypeptidase-related protein (EC 3.4.17.-) [Bd2418] [Bdellovibrio bacteriovorus] Has pfam00246, Zn_carbOpept, Zinc carboxypeptidase domain; High confidence in function and specificity. (364 aa)    
Predicted Functional Partners:
azo2295
Putative hydrolase; TREMBL:Q8EFJ6: 33% identity, 47% similarity. Probable Dihydrolipoamide acetyltransferase component of acetoin cleaving system (EC 2.3.1.12) (Acetoin dehydrogenase E2 component). Interpro:IPR000073; A/b_hydrolase (alpha/beta fold family). IPR000379; Ser_estrs. Pfam PF00561; Abhydrolase_1; 1 2a75: L-lysine exporter; Function unclear.
 
     0.926
lpdA
Dihydrolipoamide dehydrogenase. Homology to lpdA of N. meningitides of 70% (trembl|Q59099). THE BRANCHED-CHAIN ALPHA-KETO DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF ALPHA-KETO ACIDS TO ACYL-COA AND CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: BRANCHED-CHAIN ALPHA-KETO ACID DECARBOXYLASE (E1) LIPOAMIDE ACYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3) (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); Pyridine nucleotide-disulphide oxidoreductase, classI (IPR001100); biotin/Lipoyl attachment (IPR000089) [...]
   
  0.696
odhA
Probable 2-oxoglutarate dehydrogenase. Homology to odhA of A. eutrophus of 63% (sprot|ODO1_ALCEU). THE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF 2-OXOGLUTARATE TO SUCCINYL-COA & CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: 2-OXOGLUTARATE DEHYDROGENASE (E1) DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3). InterPro: Dehydrogenase E1 component (IPR001017); Transletolase (IPR005474) Tigrfam: 2oxo_dh_E1: 2-oxoglutarate dehydrogenase, E1 component Pfam: Dehydrogenase E1 component, Transketolas, pyridine binding domain [...]
  
  
  0.679
gor
Probable glutathione-disulfide reductase. Homology to gor of E. coli of 53% (sprot|GSHR_ECOLI). Maintain high levels of reduced glutathione in the cytosol. InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); NAD binding site (IPR000205); Pyridine nuclotide-disulfide oxidoreductase dimerisation doamin (IPR004099); Pyridine nucleotide-disulphide oxidoreductase, class I (IPR001100) Pfam: Pyridine nuccleotide-dusulfphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase dimerisation domain no signal peptide no TMHs; High confidence in function and [...]
     
  0.572
odhL
Probable dihydrolipoamide dehydrogenase. Homology to odhL of A. eutrophus of 68% (sprot|DLDH_ALCEU). THE BRANCHED-CHAIN ALPHA-KETO DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF ALPHA-KETO ACIDS TO ACYL-COA AND CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: BRANCHED-CHAIN ALPHA-KETO ACID DECARBOXYLASE (E1) LIPOAMIDE ACYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); Pyridine nucleotide-disulphide oxidoreductase, classI (IPR001100); Pyridine nucleotide-disulphide oxidoreducta [...]
     
  0.572
alkB
DNA-directed DNA polymerase; Alkylated DNA repair protein.Probably involved in the repair of alkylated DNA. Provides extensive resistance to alkylating agents.; High confidence in function and specificity.
       0.548
ada
Methylated-DNA--[protein]-cysteine S-methyltransferase (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase) InterPro: Methylated-DNA--protein-cysteine methyltransferase; High confidence in function and specificity.
       0.527
azo2300
Conserved hypothetical membrane protein. Homology to ORF428 of Roseateles depolymerans of 65% (trembl|Q9F206(SRS)). Pfam: Protein of unknown function (DUF1504). This family consists of several hypothetical bacterial proteins of around 440 residues in length. The function of this family is unknown. signal peptide. 10 TMHs; Conserved hypothetical protein.
 
     0.445
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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