STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phhBPHS (4-alpha-hydroxy-tetrahydropterin dehydratase) (Pterin carbinolamine dehydratase) (PCD). InterPro: Pterin 4 alpha carbinolamine dehydratase; High confidence in function and specificity. (117 aa)    
Predicted Functional Partners:
hppD
Probable 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4HPPD) (HPD) (HPPDase). Homology to hppD of Pseudomonas sp. of 56% (pir|S21209) Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2. Pfam: Glaxolase/Bleomycin resistance protein no signal peptide no TMHs; Family membership.
  
  
 0.759
azo2297
Conserved hypothetical protein. Homology to RS05664 of R.solanacearum of 53% (trembl:Q8XQC7). No domains predicted. No signal peptide or TMH reported present.
  
    0.706
azo2298
Conserved hypothetical protein. Homology to PA1356 of Pseudomonas aeruginosa of 69% (trembl|Q9I3Y8(SRS)). No domains predicted. No signal peptide or TMH reported to be present.
       0.613
aidB1
Aidb protein:-belongs to the acyl-coa dehydrogenase family. Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor. Entry name SWISSPROT:AIDB_ECOLI Prim. accession # P33224 Identities = 257/515 (49%) InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_N; 1 Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership.
   
   0.587
tyrB
Probable aromatic-amino-acid aminotransferase. Homology to tyrB of E. coli of 52% (sprot|TYRB_ECO). Is involved in biosynthesis of phe, tyr, asp and leu. Catalyse the reactiion: an aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + l-glutamate. Pfam: Aminotransferase class I and II no signal peptide no TMHs; High confidence in function and specificity.
  
  
 0.541
azo2295
Putative hydrolase; TREMBL:Q8EFJ6: 33% identity, 47% similarity. Probable Dihydrolipoamide acetyltransferase component of acetoin cleaving system (EC 2.3.1.12) (Acetoin dehydrogenase E2 component). Interpro:IPR000073; A/b_hydrolase (alpha/beta fold family). IPR000379; Ser_estrs. Pfam PF00561; Abhydrolase_1; 1 2a75: L-lysine exporter; Function unclear.
       0.447
pheA
Bifunctional chorismate mutase/prephenate dehydratase P-protein, pheA,; High confidence in function and specificity.
      
 0.402
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (40%) [HD]