gspE3 protein (Azoarcus sp. BH72) - STRING interaction network

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Score

gspE3

General secretion pathway protein E,; Specificity unclear. (606 aa)

Predicted Functional Partners:

gspF2

0.943

gspF1

0.941

pilC

0.941

pilD

0.858

gspG2

0.784

pilN

0.733

azo2088

0.717

pilZ

0.715

pilM

0.685

pilA

0.656

Your Current Organism:

Azoarcus sp. BH72

NCBI taxonomy Id: 62928
Other names: A. sp. BH72

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
azo2088	gspE3	azo2088	azo2301	Conserved hypothetical secreted protein. Homology to pp3476 of P. putida of 54% (tremble:Q88H85). no domains predicted. TMH in signal peptide. Has Signal Peptide; Conserved hypothetical protein.	General secretion pathway protein E,; Specificity unclear.	0.717
azo2088	gspF1	azo2088	azo0802	Conserved hypothetical secreted protein. Homology to pp3476 of P. putida of 54% (tremble:Q88H85). no domains predicted. TMH in signal peptide. Has Signal Peptide; Conserved hypothetical protein.	General secretion pathway protein F; Type II secretory pathway component F,; Specificity unclear.	0.658
azo2088	gspF2	azo2088	azo2096	Conserved hypothetical secreted protein. Homology to pp3476 of P. putida of 54% (tremble:Q88H85). no domains predicted. TMH in signal peptide. Has Signal Peptide; Conserved hypothetical protein.	General secretion pathway protein F,similar trembl\|Q88HD6 (39%). The general (type II) secretion pathway (GSP) within Gram-negative bacteria is a signal sequence-dependent process responsible for protein export. The process has two stages: exoproteins are first translocated across the inner membrane by the general signal-dependent export pathway (GEP), and then across the outer membrane by a species-specific accessory mechanism. InterPro (IPR001992): Bacterial type II secretion system protein. InterPro (IPR003004): Bacterial general secretion pathway protein F Pfam (PF00482): Bacterial [...]	0.959
azo2088	gspG2	azo2088	azo2097	Conserved hypothetical secreted protein. Homology to pp3476 of P. putida of 54% (tremble:Q88H85). no domains predicted. TMH in signal peptide. Has Signal Peptide; Conserved hypothetical protein.	General secretion pathway GSPG-related transmembrane protein,; Specificity unclear.	0.976
azo2088	pilA	azo2088	azo3355	Conserved hypothetical secreted protein. Homology to pp3476 of P. putida of 54% (tremble:Q88H85). no domains predicted. TMH in signal peptide. Has Signal Peptide; Conserved hypothetical protein.	Tfp structural protein; PilA encodes an unusually short (6.4 kDa)putative pilin precursor showing 100% sequence identity to the conserved N-terminus of the Pseudomonas aeruginosa type IV pilin. (Reference: Doerr et al., 1998 Molecular Microbiology); High confidence in function and specificity.	0.453
azo2088	pilC	azo2088	azo3235	Conserved hypothetical secreted protein. Homology to pp3476 of P. putida of 54% (tremble:Q88H85). no domains predicted. TMH in signal peptide. Has Signal Peptide; Conserved hypothetical protein.	Type 4 pilus biogenesis protein; Pilus assembly protein PilC is a component of the pilus biogenesis apparatus, similarity to pir\|B35384 (50%). This apparatus is responsible for the stabilization, translocation and assembly of the monomeric pilin subunits into the pilus organelle. InterPro (IPR001992): Bacterial type II secretion system protein. InterPro (IPR003004): Bacterial general secretion pathway protein F Pfam (PF00482): Bacterial type II secretion system protein TMHMM reporting three TMH; High confidence in function and specificity.	0.689
azo2088	pilD	azo2088	azo3236	Conserved hypothetical secreted protein. Homology to pp3476 of P. putida of 54% (tremble:Q88H85). no domains predicted. TMH in signal peptide. Has Signal Peptide; Conserved hypothetical protein.	Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	0.573
gspE3	azo2088	azo2301	azo2088	General secretion pathway protein E,; Specificity unclear.	Conserved hypothetical secreted protein. Homology to pp3476 of P. putida of 54% (tremble:Q88H85). no domains predicted. TMH in signal peptide. Has Signal Peptide; Conserved hypothetical protein.	0.717
gspE3	gspF1	azo2301	azo0802	General secretion pathway protein E,; Specificity unclear.	General secretion pathway protein F; Type II secretory pathway component F,; Specificity unclear.	0.941
gspE3	gspF2	azo2301	azo2096	General secretion pathway protein E,; Specificity unclear.	General secretion pathway protein F,similar trembl\|Q88HD6 (39%). The general (type II) secretion pathway (GSP) within Gram-negative bacteria is a signal sequence-dependent process responsible for protein export. The process has two stages: exoproteins are first translocated across the inner membrane by the general signal-dependent export pathway (GEP), and then across the outer membrane by a species-specific accessory mechanism. InterPro (IPR001992): Bacterial type II secretion system protein. InterPro (IPR003004): Bacterial general secretion pathway protein F Pfam (PF00482): Bacterial [...]	0.943
gspE3	gspG2	azo2301	azo2097	General secretion pathway protein E,; Specificity unclear.	General secretion pathway GSPG-related transmembrane protein,; Specificity unclear.	0.784
gspE3	pilA	azo2301	azo3355	General secretion pathway protein E,; Specificity unclear.	Tfp structural protein; PilA encodes an unusually short (6.4 kDa)putative pilin precursor showing 100% sequence identity to the conserved N-terminus of the Pseudomonas aeruginosa type IV pilin. (Reference: Doerr et al., 1998 Molecular Microbiology); High confidence in function and specificity.	0.656
gspE3	pilC	azo2301	azo3235	General secretion pathway protein E,; Specificity unclear.	Type 4 pilus biogenesis protein; Pilus assembly protein PilC is a component of the pilus biogenesis apparatus, similarity to pir\|B35384 (50%). This apparatus is responsible for the stabilization, translocation and assembly of the monomeric pilin subunits into the pilus organelle. InterPro (IPR001992): Bacterial type II secretion system protein. InterPro (IPR003004): Bacterial general secretion pathway protein F Pfam (PF00482): Bacterial type II secretion system protein TMHMM reporting three TMH; High confidence in function and specificity.	0.941
gspE3	pilD	azo2301	azo3236	General secretion pathway protein E,; Specificity unclear.	Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	0.858
gspE3	pilM	azo2301	azo3650	General secretion pathway protein E,; Specificity unclear.	Type 4 fimbrial biogenesis protein PilM, similarity to trembl\|Q82SK1 (56%)and to pir\|S77726 (47%). Four genes,pilM-P, encode the necessary proteins and pilM is required for the assembly of the type IV fimbriae in Pseudomonas aeruginosa; Specificity unclear.	0.685
gspE3	pilN	azo2301	azo3649	General secretion pathway protein E,; Specificity unclear.	Type 4 fimbrial biogenesis protein PilN, similarity to trembl\|Q82SK2(51%)and to pir\|S77727(42%). In P. aeruginosa PilN was found to be required for fimbrial biogenesis by complementation studies using twitching motility and sensitivity to fimbrial-specific phage as indicators of the presence of functional fimbriae. SignalP reporting signal peptide; Specificity unclear.	0.733
gspE3	pilZ	azo2301	azo1597	General secretion pathway protein E,; Specificity unclear.	Type IV pilus biogenesis protein PilZ, 56% identity to TrEMBL;Q87YH3, Q8PBU4. Has PF07238, Type IV pilus assembly protein PilZ; IPR009875; This family consists of several bacterial type IV pilus assembly proteins. PilZ is thought to have a cytoplasmic location and be essential for type 4 fimbrial biogenesis but its exact function is unknown.	0.715
gspF1	azo2088	azo0802	azo2088	General secretion pathway protein F; Type II secretory pathway component F,; Specificity unclear.	Conserved hypothetical secreted protein. Homology to pp3476 of P. putida of 54% (tremble:Q88H85). no domains predicted. TMH in signal peptide. Has Signal Peptide; Conserved hypothetical protein.	0.658
gspF1	gspE3	azo0802	azo2301	General secretion pathway protein F; Type II secretory pathway component F,; Specificity unclear.	General secretion pathway protein E,; Specificity unclear.	0.941
gspF1	gspG2	azo0802	azo2097	General secretion pathway protein F; Type II secretory pathway component F,; Specificity unclear.	General secretion pathway GSPG-related transmembrane protein,; Specificity unclear.	0.737