STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msbA1Lipid A export ATP-binding/permease protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (588 aa)    
Predicted Functional Partners:
azo0646
Toxin secretion ABC transporter permease and ATP-binding protein; HlyB-family protein. Similar to TREMBL:Q7WBM7 (50% identity); TREMBL:Q9KKL9 (41% identity); SWISSPROT:P18770 (28% identity). Pfam (PF00005): ABC transporter. Pfam (PF00664): ABC transporter transmembrane region. TMHMM reporting four transmembrane helices. TC (3.A.1.109.3): LapA adhesin protein exporter, LapB; High confidence in function and specificity.
 
 
0.861
azo2315
Conserved hypothetical tyrosine/serine phosphatase,; Conserved hypothetical protein.
       0.778
azo2318
Hypothetical membrane protein. homology to rsc2204 of R.solanacearum of 28% (trembl|Q8XXB2(SRS)). no domains predicted. no signal peptide. 10 TMHs.
       0.778
azo2319
Glycosyltransferase; CMP-N-acetylneuraminate-beta-galactosamide-alpha- 23-sialyltransferase (EC 2.4.99.4) (Beta-galactoside alpha-23-sialyltransferase) (Alpha 23-ST) (Gal-NAc6S) (Gal-beta-13-GalNAc-alpha-23-sialyltransferase) (ST3GalIA) (ST3O) (ST3GalA.1) (SIAT4-A) (ST3Gal I). IT MAY BE RESPONSIBLE FOR THE SYNTHESIS OF THE SEQUENCE NEUAC-ALPHA-23-GAL-BETA-13-GALNAC- FOUND ON SUGAR CHAINS O-LINKED TO THR OR SER AND ALSO AS A TERMINAL SEQUENCE ON CERTAIN GANGLIOSIDES. SIAT4-A AND SIAT4-B SIALYLATE THE SAME ACCEPTOR SUBSTRATES BUT EXHIBIT DIFFERENT KM VALUES; Specificity unclear.
       0.775
azo2314
Glycosyltransferase; Family membership.
       0.773
azo2317
Hypothetical protein predicted by Glimmer/Critica. No homology of the entire protein to the data bank. no dmains predicted. no signal peptide. no TMHs.
       0.773
azo2320
Conserved hypothetical protein. Homology to Rsph03001342 of Rhodobacter sphaeroides of 39% (gi|22957735|ref|ZP_00005426.1|(NBCI ENTREZ)). Has PF04230, Polysaccharide pyruvyl transferase;IPR007345 PS_pyruv_trans; Pyruvyl-transferases involved in peptidoglycan-associated polymer biosynthesis. CsaB in Bacillus anthracis is necessary for the non-covalent anchoring of proteins containing an SLH (S-layer homology) domain to peptidoglycan-associated pyruvylated polysaccharides. WcaK and AmsJ are involved in the biosynthesis of colanic acid in Escherichia coli and of amylovoran in Erwinia amyl [...]
       0.773
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.667
azo1821
Conserved hypothetical membrane protein. Homology to ebA6882 of Azoarcus sp. EbN1 of 74% (gnl|keqq|eba:ebA6882(KEGG)). Domian structure: 373 aa -599 aa AAA ATPase; 638 aa - 726 aa HATPase_c; 750 aa - 877 aa Rec InterPro: ABC transporter (IPR003439); AAA ATPase superfamily (IPR003593); ABC transporter transmembrane region (IPR001140); ATP/GTP-binding site motif A ((P-loop) (IPR001687); (Response regulator reciver (IPR001789); Histidine kinase-, DNA gyrase B-, phytochrome-like ATPase (IPR003594) Pfam: ABC-transporter, ABC transmembrane region; Response regulator reciver domain. no signal [...]
  
 
0.648
azo2638
Conserved hypothetical ATPase. Homology to rsc1961 of R. solanacearum of 37% (trembl|Q8XY02). Pfam: Atpase familly associated with various cellular activities (domaine 1 from 300 aa to 499 aa, domaine 2 from 543 to 723 aa). no signal peptide. no TMHs; Conserved hypothetical protein.
   
 0.648
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.