STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2386Conserved hypothetical membrane protein. Homology to BB4221 of Bordetella bronchiseptica of 32% (trembl|Q7WFQ0). Has PF07331, Protein of unknown function (DUF1468);IPR009936;This family consists of several hypothetical bacterial proteins of around 150 residues in length. The function of this family is unknown. Signal peptide. 3 TMHs; Conserved hypothetical protein. (147 aa)    
Predicted Functional Partners:
azo2387
Conserved hypothetical membrane protein. Homology to an orf of R. palustris of 63% (tremblnew|CAE27761(SRS)). Has PF01970, Integral membrane protein DUF112;IPR002823:Members of this prokaryotic family have no known function. no signal peptide. 10 TMHs; Conserved hypothetical protein.
 
 
 0.990
azo1638
Putative exported protein, 39% identity (54% similarity)to TrEMBL;Q7VUI5 TrEMBL;Q7WNJ8. Has PF03401;Bordetella uptake gene (bug) product;(IPR005064)These probable extra-cytoplasmic solute receptors are strongly overrepresented in several beta-proteobacteria. SIgnal Peptide Present. No TMH reported present; Specificity unclear.
 
  
 0.950
fsr
A gene conferring resistance to fosmidomycin (Fs) encode a putative polypeptide of 406 amino acids (aa) with a molecular weight of 43303 in E.coli. 23% similarity to B. japonicum fsr. A comparison between the aa sequence of Fsr and sequences in a protein database revealed 18% homology to the bacterial drug-export proteins that mediate resistance to tetracycline and chloramphenicol. Hydropathy analysis of the Fsr protein revealed twelve putative transmembrane segments. Fsr does not have any direct effect on the biosynthesis of isoprenoid in E. coli, and that the mechanism for FsR involv [...]
  
     0.673
azo2388
Hypothetical membrane protein. no homology of the entire protein to the data bank. no domain predicted. no signal peptide. 4 TMHs.
       0.661
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
     
  0.505
azo2384
Conserved hypothetical ApbE family protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.
       0.431
azo2385
Hypothetical membrane protein. No homology of the entire protein to the data bank. No domains predicted. signal peptide. 3 TMHs.
       0.431
soxE
Putative sulfide dehydrogenase, cytochrome subunit. Homology to fccA of C. limicola of 26% (sprot|CYSD_CHLLT(SRS)) InterPro: Cytochrome c class I (IPR003088); cytochrome c class IC (IPR008168) Pfam: Cytochrome C signal peptide no TMHs.
  
     0.416
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.