Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tauAPutative sulfonate transport system, periplasmic component; Part of the ABC transporter complex tauABC involved in taurine as a sulfur source import. Similar to the putative aliphatic sulfonates periplasmic-binding protein tauA in E.coli. Probably also involved in nitrate and bicarbonate transport; Function unclear. (341 aa)    
Predicted Functional Partners:
tauB
Putative sulfonate transport system, ATP-binding protein; Part of the ABC transporter complex tauABC involved in taurine import as a sulfur source.Probably responsible for energy coupling to the transport system.Similar to the aliphatic sulfonate transport membrane protein, tauB in E.coli. Probably also involved in nitrate and bicarbonate transport; High confidence in function and specificity.
 
 0.981
tauC
Putative sulfonate transport system, permease protein; Part of the ABC transporter complex tauABC involved in taurine import as sulfur source. Probably responsible for the translocation of the substrate across the membrane.Similar to the aliphatic sulfonate permease protein, tauC in E.coli. Probably also involved in nitrate and bicarbonate transport; High confidence in function and specificity.
 
 0.976
ssuC
Part of the ABC transporter complex ssuABC involved in aliphatic sulfonates import. Probably responsible for the translocation of the substrate across the membrane.26% Similar to the aliphatic sulfonates permease protein, ssuC in E.coli. SWISSPROT:SSUC_ECOLI: P75851 InterPro:IPR000515; BPD_transp. Pfam:PF00528; BPD_transp; 1. InterPro:PF00528: Binding-protein-dependent transport systems inner membrane component. TMhelix:6; Specificity unclear.
 
 0.957
nasE
Nitrate transport permease protein nasE. 41% Similar to the nitrate permease protein, nrtB in Synechococcus sp.Part of the ABC transporter complex nrtBCD involved in nitrate import.Probably responsible for the translocation of the substrate across the membrane. SWISSPROT:NRTB_SYNP7.P38044. InterPro:IPR000515; BPD_transp.IPR005889; NtrB. Pfam:PF00528; BPD_transp; 1. TIGRFAMs:TIGR01183; ntrB; 1. TMHelix: 4; High confidence in function and specificity.
 
 0.953
nasD
Putative nitrate transport system, ATP-binding protein; Part of the ABC transporter complex nasFED involved in nitrate import. 64% Similar to the nitrate transport membrane protein, nasD in Klebsella oxytoca. Probably responsible for energy coupling to the transport system. SWISSPROT:NASD_KLEOX.P39459. InterPro:IPR003593; AAA_ATPase.IPR003439; ABC_transporter.IPR005890; NtrCD. Pfam:PF00005; ABC_tran; 1. TIGRFAMs:TIGR01184; ntrCD; 1; High confidence in function and specificity.
 
 0.923
azo3513
Putative aliphatic sulfonates transport system,ATP-binding protein; Region start changed from 3855391 to 3855571 (-180 bases).
 
 0.920
azo2910
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8FZX0 (58% identity); TREMBL:Q8U6Y9 (59% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...]
    
 0.737
yhbG
Probable ABC transporter ATP-binding protein HI1148. ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. TREMBL:Q7NST9: 64% identity,75% similarity InterPro: IPR003593; AAA_ATPase. IPR003439; ABC_transporter. IPR000767; Disease_resist. IPR003016; Lipoyl_BS. Pfam PF00005; ABC_tran; 1 mobB: molybdopterin-guanine dinucleoti TMH's present 0; High confidence in function and specificity.
     
 0.690
azo2902
Probable integral membrane protein; TREMBL:Q8XWQ6: 39% identity, 56% similarity Hypothetical protein HI1703. InterPro: IPR005495; YjgP_YjgQ. Pfam: PF03739;Pfam :DUF214:Predicted permease Members of this family are predicted integral membrane proteins of unknown function. They are about 350 amino acids long, contain about 6 transmembrane regions and may be permeases, although there is no verification of this. subcellular location:integral membrane protein (potential). similarity:strong, to h.influenzae hi1703 2a69: Auxin Efflux Carrier TMHMM predicted 6 transmembrane helices; Conserved [...]
     
  0.684
azo2903
Conserved hypothetical membrane protein. TREMBL:Q8XWQ7: 40% identity; 55% similarity: probable integral membrane protein InterPro:IPR005495; YjgP_YjgQ. Pfam:PF03739; YjgP_YjgQ :UbiA : UbiA prenyltransferase family Pfam:DUF112:Integral membrane protein DUF112 Signal peptide present (Signal P predicted). Transmembrane helices: 5 (TMHMM predicted); Conserved hypothetical protein.
     
  0.684
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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