Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
cysKCysteine synthase A,; High confidence in function and specificity; Belongs to the cysteine synthase/cystathionine beta- synthase family. (326 aa)    
Predicted Functional Partners:
nifP
Serine acetyltransferase (EC 2.3.1.30). Homology to nifP of A. chrooccum of 58% (pir|D43706). PROBABLE SERINE ACETYLTRANSFERASE REQUIRED FOR OPTIMIZING THE EXPRESSION OF NITROGENASE ACTIVITY. NIFP MAY BE REQUIRED TO BOOST RATES OF SYNTHESIS OR INTRACELLULAR CONCENTRATIONS OF CYSTEINE OR METHIONINE. InterPro: Bacterial transferase hexapeptide repeat (IPR001451) no signal peptide no TMHs; High confidence in function and specificity.
 
 0.986
cysE
Probable serine acetyltransferase (EC 2.3.1.30). Homology to cysE of B. subtilis of 48% (sprot|CYSE_BACSU). no signal peptide no TMHs; Family membership.
 
 0.984
srpH
Probable serine O-acetyltransferase plasmid (EC 2.3.1.30) (SAT). Homology to srpH of Synechococcus of 55% (sprot|SRPH_SYNP7) no signal peptide no TMHs; High confidence in function and specificity.
 
 0.983
metZ
Cys/Met metabolism pyridoxal-phosphate-dependent enzyme; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 0.980
cysI
Putative sulfite reductase; 49% Fd-NiR.IPR011255; NiR_SiRalpha_1/3.IPR006067; Nir_Sir_4Fe4S.IPR005117; NiR_SiR_beta_fer. Pfam:PF01077; NIR_SIR; 2.PF03460; NIR_SIR_ferr; 2; High confidence in function and specificity.
  
 
 0.937
metH
Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.926
acyH
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.889
sseA
SseA: putative thiosulfate sulfurtransferase (rhodanese-like protein) [EC:2.8.1.1]. This protein transfers a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity (130-fold lower). Its participation in detoxification of cyanide may be small. May be involved in the enhancement of serine sensitivity. Probable 3-mercaptopyruvate sulfurtransferase (EC 2.8.1.2) (Rhodanese- like protein) (MST). InterPro: Rhodanese/cdc25 fold; High confidence in function and specificity.
  
 
 0.889
azo3380
Conserved hypothetical transaminase; Region start changed from 3714581 to 3714479 (102 bases).
    
 0.883
boxA
Benzoyl-CoA oxygenase component A. 84% 4Fe4S_ferredoxin. IPR001709; FPN_cyt_redctse. IPR001433; Oxred_FAD/NAD(P). Pfam:PF00037; Fer4; 2. PF00175; NAD_binding_1; 1; High confidence in function and specificity.
  
 
 0.880
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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