STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo2401Conserved hypothetical secreted protein. Homology to rsp0812 of R. solanacearum of 30% (trembl|Q8XRL9). no damians predicted. signal peptide. no TMHs; Conserved hypothetical protein. (189 aa)    
Predicted Functional Partners:
barA
Putative sensor-regulator protein,; Specificity unclear.
 
     0.854
azo2400
Putative TonB outer membrane receptor protein.31% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1. Signal peptide present; Function unclear.
 
     0.833
wspR2
Probable two-component response regulator,; High confidence in function and specificity.
       0.774
irgA2
Putative TonB-dependent receptor; 24% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1. Signal peptide present; High confidence in function and specificity.
 
     0.505
azo2404
Hypothetical secreted protein. no homology of the entire protein to the data bank. no domains predicted. signal peptide. no TMHs.
       0.481
irgA1
Putative TonB-dependent receptor; 23% TonB_boxC. Pfam:PF00593; TonB_dep_Rec; 1; High confidence in function and specificity.
 
     0.444
azo0409
Putative anti-sigma factor antagonists (STAS domain protein), STAS. Pfam: PF01740; STAS. The STAS (Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C-terminal region of sulphate transporters and bacterial anti-sigma factor antagonists. It has been suggested that this domain may have a general NTP binding function; Function unclear.
  
     0.423
azo2584
Conserved hypothetical protein; Similar to TREMBL:Q7NTT5 (32% identity).
  
     0.416
azo2482
Putative hybrid sensor and regulator; Gene function unknown, no significant homology to proteins of known function. Typical domains for hybrid sensor and regulator are found. InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR001789 Response_reg. IPR008207 Hpt. IPR000014 PAS_domain. IPR001610 PAC. Pfam: PF00072 Response_reg. PF02518 HATPase_c. PF00512 HisKA. PF00989 PAS. PF00785 PAC. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00448 REC. SM00091 PAS SM00086 PAC. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal pepti [...]
 
     0.414
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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