STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ohrProbable organic hydroperoxide resistance protein. Homology to ohr of X. campestris of 50% (SWISSPROT:OHR_XANAC). Organic hydroperoxide detoxification protein. Confers increased resistance to tert-butyl hydroperoxide killing. InterPro: OsmC-like protein (IPR003718) Pfam: OsmC-like protein no signal peptide no TMH; High confidence in function and specificity. (145 aa)    
Predicted Functional Partners:
azo3768
Putative catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
 
  
 0.634
azo2408
Hypothetical sensor protein.
  
    0.582
yafB
25-diketo-D-gluconic acid reductase B (EC 1.1.1.274) (25-DKG reductase B) (25-DKGR B) (25DKGR-B) (AKR5D). TREMBL:Q8Y090: 67% identity, 78% similarity. Catalyzes the reduction of 25-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG) (By similarity). subunit:monomer (by similarity). subcellular location:cytoplasmic (by similarity). 2-keto-l-gulonic acid is a key intermediate in the production of l-ascorbic acid (vitamin c). belongs to the aldo/keto reductase family InterPro:IPR001395; Aldo/ket_red. Pfam:PF00248; aldo_ket_red; 1. PRINTS PR00069; ALDKETRDTAS ribH: riboflavin sy [...]
  
  
 0.569
prkA
Putative serine protein kinase. Homology to prkA of Bacillus subtilis of 32% (gnl|keqq|bsu:BG10804). Pfam: PrkA serine kinase. This is a family of PrkA bacterial and archaeal serine kinases approximately 630 residues long. PrkA possesses the A-motif of nucleotide-binding proteins and exhibits distant homology to eukaryotic protein kinases. Note that many family members are hypothetical. Interpro: IPR010650 PrkA serine kinase. No signal peptide. No TMHs.,; Family membership.
   
    0.512
azo0098
Conseved hypothetical membrane protein. Homology to RSO2271 of R. solanacearum of 36% (trembl|Q8Y3B1(SRS)). Pfam: Lysin motif (SM00257) This domain is about 40 residues long and is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. No signal peptide 1 TMH; Conserved hypothetical protein.
  
  
 0.510
azo2406
Conserved hypothetical pyruvate ferredoxin/flavodoxin oxidoreductase. Homology to bb4375 of B. bronchiseptica (trembl|Q7WFA5). CATALYZES THE FERREDOXIN-DEPENDENT OXIDATIVE DECARBOXYLATION OF ARYLPYRUVATES (BY SIMILARITY). Pfam: Pyruvate ferredoxin/flavodoxin oxidoreductase. no signal peptide. no TMHs; Conserved hypothetical protein.
       0.499
azo2450
Putative two-component system sensor protein,; Function unclear.
   
  
 0.486
azo1490
Conserved hypothetical signaling protein. Homology to ebA6472 Azoarcus sp. EbN1 of 36% (gnl|keqq|eba:ebA6472(KEGG)). InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. IPR001789 Response_reg. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF01590 GAF domain. PF00563 EAL domain. PF00072 Response_reg. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain. No signal peptide. No TMHs; Conserved hypothetical protein.
   
  
 0.481
azo0426
GGDEF/PAS-domain containing protein.
   
    0.476
azo1256
Putative serin/threonine protein kinase, only very low similarity to SWISSPROT: sprot|PKSC_STRCO (13% Streptomyces coelicolor, serine/threonine protein kinase PksC (EC 2.7.11.1)) / TREMBL: trembl|Q9S478 (13% Myxococcus xanthus, Pkn4). Pfam: PF00069 Pkinase. SMART:SM00221 STYKc (Protein kinase; unclassified specificity). SM00065 GAF (Domain present in phytochromes and cGMP-specific phosphodiesterases); Family membership.
   
    0.476
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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