STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
azo2409Conserved hypothetical sodium:solute sympoter. Homology to bb3915 of B. bronchiseptica of 57% (trembl|Q7WCM0). Sodium/substrate symport (or co-transport) is a widespread mechanism of solute transport across cytoplasmic membranes of pro- and eukaryotic cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient. The solutes transported may be sugars, amino acids, nucleosides, inositols, vitamins,urea or anions, depending on the system. Tigrfam: sss: SSS sodium so [...] (686 aa)    
Predicted Functional Partners:
azo2201
Putative nucleotidyltransferase,; Conserved hypothetical protein.
 
  
 0.868
azo1151
Conserved hypothetical membrane protein. Homology to vv11244 of V. vulnificus of 42% (trembl|Q8DCZ3(SRS)) no domains predicted no signal peptide 2 TMHs; Conserved hypothetical protein.
 
    0.808
azo1148
Conserved hypothetical membrane protein. Homology to ws0602 of W. succinogenes of 63% (trembl|Q7MSB5(SRS)) no domains predicted no singal peptide 2 TMHs; Conserved hypothetical protein.
 
    0.804
azo2410
DNA polymerase III epsilon chain-like protein (EC 2.7.7.7). DNA POLYMERASE III IS A COMPLEX MULTICHAIN ENZYME RESPONSIBLE FOR MOST OF THE REPLICATIVE SYNTHESIS IN BACTERIA. THE EPSILON SUBUNIT CONTAIN THE EDITING FUNCTION AND IS A PROOFREADING 3-5 EXONUCLEASE (BY SIMILARITY). dnaq: DNA polymerase III epsilon sub; Family membership.
 
     0.775
azo0681
Conserved hypothetical membrane protein. Homology to PP2796 of P. putida of 44% (trembl|Q88J53) PF04341,Protein of unknown function, DUF485;IPR007436;This family includes several putative integral membrane proteins. signal peptide 1 TMHs; Conserved hypothetical protein.
  
  
 0.666
azo0977
Conserved hypothetical membrane protein. Homology to XCC4058 of Xanthomonas campestris of 55% (trembl|Q8P3L3) Has PF04341, Protein of unknown function,DUF485; IPR007436;This family includes several putative integral membrane proteins. no signal peptide 1 TMH; Conserved hypothetical protein.
  
  
 0.666
acsB
Probable acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.505
azo2202
Probable DNA polymerase III, epsilon subunit,23% Identity to TrEMBL;Q8KDK8. Has EXOIII,SMART;SM00479;IPR006054, DnaQ;This family includes a variety of exonuclease proteins, such as ribonuclease T and the epsilon subunit of DNA polymerase III. Ribonuclease T is responsible for the end-turnover of tRNA,and removes the terminal AMP residue from uncharged tRNA. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria, and also exhibits 3' to 5' exonuclease activity.
  
    0.451
azo2412
Sensor histidine kinase mtrB (EC 2.7.3.-). Member of the two-component regulatory system mtrA/mtrB. Seems to function as a membrane-associated protein kinase that phosphorylates mtrA in response to environmental signals (By similarity). TREMBLnew:AAS80811; TREMBL:Q8PEZ5, 42% identity, 59% similarity; Pfam: Histidine kinase _,Phosphoacceptor domain. TIGRFAM: sss: sodium solute transporter sup. TMHMM predicted transmembrane helices. sss: SSS sodium solute transporter sup; Specificity unclear.
     
 0.439
yycF
Transcriptional regulatory protein yycF. Member of the two-component regulatory system yycG/yycF involved in the regulation of the ftsAZ operon. Binds to the ftsAZ P1 promoter sequence. Similar to SWISSPROT: sprot|YYCF_BACSU (50% Bacillus subtilis, transcriptional regulatory protein YycF) / sprot|PHOP_BACSU (47% Bacillus subtilis, alkaline phosphatase synthesis transcriptional regulatory protein PhoP) InterPro: IPR001789 Response_reg. Pfam: PF00072 Response_reg; Specificity unclear.
       0.429
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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