Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nahR1LysR-type transcriptional regulator NahR. Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes. Belongs to the LysR family of transcriptional regulators. Similar to SWISSPROT: sprot|NAHR_PSEPU (40% Pseudomonas putida, hth-type transcriptional activator NahR) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif; Specificity unclear. (302 aa)    
Predicted Functional Partners:
nagI
Gentisate 1,2-dioxygenase; Involved in catabolism of naphthalene via gentisate to fumarate and pyruvate. NagI is a gentisate 1,2-dioxygenase which converts gentisate to maleylpyruvate. Similar to TREMBL:O86041 (66% identity); TREMBL:Q8X655 (30% identity); TREMBL:Q8Y0F7 (33% identity); High confidence in function and specificity.
 
     0.628
nahG
Salicylate hydroxylase (EC 1.14.13.1) (Salicylate 1-monooxygenase). Similar to TREMBL:Q8Z5B1 (62% identity); TREMBL:Q8X657 (62% identity); TREMBL:Q8ZNM3 (62% identity). Pfam (PF01360): Monooxygenase. TMHMM reporting one transmembrane helix; High confidence in function and specificity.
 
   
 0.536
azo1835
Transcriptional regulator, LysR family,; Specificity unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.508
azo1543
Transcriptional regulator, LysR family,; Specificity unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.501
gstR2
Probable transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family.
  
     0.471
rpoA
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.462
bdhR
Transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family.
  
     0.426
rpoB
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.423
rpoZ
DNA-directed RNA polymerase; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.419
azo2367
Transcriptional regulator, LysR family,; Function unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.418
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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